Anti-IRX4抗体(ab123542)
Key features and details
- Rabbit polyclonal to IRX4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IRX4抗体 -
描述
兔多克隆抗体to IRX4 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Cow, Dog, Pig, Macaque monkey, Orangutan -
免疫原
Synthetic peptide corresponding to Human IRX4 aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab139538) -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab123542于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 54 kDa).
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说明 |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 54 kDa). |
靶标
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功能
Likely to be an important mediator of ventricular differentiation during cardiac development. -
组织特异性
Predominantly expressed in cardiac ventricles. -
序列相似性
Belongs to the TALE/IRO homeobox family.
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 373974 Chicken
- Entrez Gene: 50805 Human
- Entrez Gene: 50916 Mouse
- Entrez Gene: 306655 Rat
- Omim: 606199 Human
- SwissProt: Q9YGS0 Chicken
- SwissProt: P78413 Human
- SwissProt: Q2NL64 Human
see all -
别名
- Homeodomain protein IRXA3 antibody
- Iroquois homeobox protein 4 antibody
- Iroquois-class homeodomain protein IRX-4 antibody
see all
图片
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Anti-IRX4 antibody (ab123542) at 1 µg/ml + Human heart tissue lysate - total protein (ab29431) at 25 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 54 kDa
Observed band size: 54 kDa
Exposure time: 20 minutes
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab123542 被引用在 2 文献中.
- Jia Z et al. 1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells. Cell Death Dis 11:670 (2020). PubMed: 32820157
- Ward MC & Gilad Y A generally conserved response to hypoxia in iPSC-derived cardiomyocytes from humans and chimpanzees. Elife 8:N/A (2019). PubMed: 30958265