概述

  • 产品名称Anti-IRTA2抗体
    参阅全部 IRTA2 一抗
  • 描述
    兔多克隆抗体to IRTA2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal region of Human IRTA2.

  • 阳性对照
    • Jurkat cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab110603 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 106 kDa.

靶标

  • 功能May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.
  • 组织特异性Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B cells and down-regulated in germinal center cells (at protein level).
  • 疾病相关Note=A chromosomal aberration involving FCRL5 has been found in cell lines with 1q21 abnormalities derived from Burkitt lymphoma. Duplication dup(1)(q21q32).
  • 序列相似性Contains 8 Ig-like C2-type (immunoglobulin-like) domains.
  • 结构域Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM).
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BXMAS1 antibody
    • CD307 antigen antibody
    • CD307e antibody
    • Fc receptor homolog 5 antibody
    • Fc receptor like 5 antibody
    • Fc receptor-like protein 5 antibody
    • FcR-like protein 5 antibody
    • FcRH5 antibody
    • FcRL5 antibody
    • FCRL5_HUMAN antibody
    • Immune receptor translocation-associated protein 2 antibody
    • Immunoglobulin receptor translocation associated gene 2 protein antibody
    • Immunoglobulin superfamily receptor translocation associated gene 2 protein antibody
    • IRTA2 antibody
    • UNQ503/PRO820 antibody
    see all

Anti-IRTA2 antibody 图像

  • All lanes : Anti-IRTA2 antibody (ab110603) at 1/500 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate with blocking peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 106 kDa

Anti-IRTA2 antibody (ab110603)参考文献

ab110603 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110603.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"