Anti-Iroquois homeobox protein 3抗体(ab111180)

概述

  • 产品名称Anti-Iroquois homeobox protein 3抗体
    参阅全部 Iroquois homeobox protein 3 一抗
  • 描述
    兔多克隆抗体to Iroquois homeobox protein 3
  • 特异性Detects endogenous levels of total Iroquois homeobox protein 3.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthesized peptide derived from an internal region of Human Iroquois homeobox protein 3.

  • 阳性对照
    • Human breast carcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.88% Sodium chloride, 49.1% PBS
    Note: PBS (without Mg2+ and Ca2+)
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111180 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.
  • 序列相似性Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI894186 antibody
    • Homeodomain protein IRXB1 antibody
    • Iroquois class homeodomain protein IRX 1 antibody
    • Iroquois homeobox 3 antibody
    • Iroquois homeobox protein 3 antibody
    • Iroquois-class homeodomain protein irx-3 antibody
    • IRX 1 antibody
    • irx3 antibody
    • IRX3_HUMAN antibody
    • IRXB1 antibody
    see all

Anti-Iroquois homeobox protein 3 antibody 图像

  • ab111180 at 1/50 dilution staining Iroquois homeobox protein 3 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide

Anti-Iroquois homeobox protein 3 antibody (ab111180)参考文献

ab111180 has not yet been referenced specifically in any publications.

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