Anti-IRAK2抗体(ab25957)

概述

  • 产品名称Anti-IRAK2抗体
    参阅全部 IRAK2 一抗
  • 描述
    兔多克隆抗体to IRAK2
  • 特异性ab25957 recognises IRAK2 but does not cross-react with IRAK.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Synthetic peptide, corresponding to 16 C terminal amino acids of Mouse IRAK2a isoform. This sequence is common to all four isoforms.

  • 阳性对照
    • Whole cell lysate from A-20 cells.

性能

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应用

Our Abpromise guarantee covers the use of ab25957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 65 kDa.

靶标

  • 功能Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
  • 组织特异性Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
    Contains 1 death domain.
    Contains 1 protein kinase domain.
  • 结构域The protein kinase domain is predicted to be catalytically inactive.
  • Information by UniProt
  • 数据库链接
  • 别名
    • il1rak2 antibody
    • Interleukin 1 receptor associated kinase 2 antibody
    • Interleukin 1 receptor associated kinase like 2 antibody
    • Interleukin-1 receptor-associated kinase-like 2 antibody
    • IRAK 2 antibody
    • IRAK-2 antibody
    • Irak2 antibody
    • IRAK2_HUMAN antibody
    • MGC150550 antibody
    see all

Anti-IRAK2 antibody 图像

  • Lane 1 : Anti-IRAK2 antibody (ab25957) at 0.5 µg/ml
    Lane 2 : Anti-IRAK2 antibody (ab25957) at 1 µg/ml
    Lane 3 : Anti-IRAK2 antibody (ab25957) at 2 µg/ml

    Lane 1 : A-20 whole cell lysate
    Lane 2 : A-20 whole cell lysate
    Lane 3 : A-20 whole cell lysate


    Predicted band size : 65 kDa

Anti-IRAK2 antibody (ab25957)参考文献

ab25957 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 25 µg
Gel Running Conditions Reduced Denaturing
Sample Mouse Cell lysate - whole cell (LIVER)
Specification LIVER
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 23°C
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提交于 Nov 10 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"