Anti-IPO11抗体- N-terminal (ab93475)

概述

  • 产品名称Anti-IPO11抗体- N-terminal
    参阅全部 IPO11 一抗
  • 描述
    兔多克隆抗体to IPO11 - N-terminal
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the N terminal region of Human IPO11 conjugated to KLH (NP_057422.3).

  • 阳性对照
    • Hela cell line lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab93475 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab93475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 113 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12.
    • 序列相似性Belongs to the importin beta family.
      Contains 15 HEAT repeats.
      Contains 1 importin N-terminal domain.
    • 细胞定位Cytoplasm. Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Imp11 antibody
      • Importin 11 antibody
      • Importin-11 antibody
      • IPO11 antibody
      • IPO11_HUMAN antibody
      • Ran binding protein 11 antibody
      • Ran-binding protein 11 antibody
      • RanBP11 antibody
      • SLRN antibody
      • Synleurin antibody
      see all

    Anti-IPO11 antibody - N-terminal 图像

    • Anti-IPO11 antibody - N-terminal (ab93475) at 1/100 dilution + HeLa cell line lysates at 35 µg

      Predicted band size : 113 kDa

    Anti-IPO11 antibody - N-terminal (ab93475)参考文献

    ab93475 has not yet been referenced specifically in any publications.

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