重组Anti-IPL-1/STK13/Aurora C抗体[EP1011Y] (ab46783)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EP1011Y] to IPL-1/STK13/Aurora C
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-IPL-1/STK13/Aurora C抗体[EP1011Y]
参阅全部 IPL-1/STK13/Aurora C 一抗 -
描述
兔单克隆抗体[EP1011Y] to IPL-1/STK13/Aurora C -
宿主
Rabbit -
特异性
This antibody is not recommended in tissue lysate testing.
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经测试应用
适用于: WBmore details
不适用于: ICC/IF -
种属反应性
与反应: Human -
免疫原
Synthetic peptide within Human IPL-1/STK13/Aurora C aa 1-100 (N terminal). The exact sequence is proprietary.
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阳性对照
- HepG2 cell lysate
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EP1011Y -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab46783于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
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说明 |
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WB
1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa). |
靶标
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功能
May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis. -
组织特异性
Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase. -
疾病相关
Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA. -
序列相似性
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
Contains 1 protein kinase domain. -
细胞定位
Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis. - Information by UniProt
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数据库链接
- Entrez Gene: 6795 Human
- Omim: 603495 Human
- SwissProt: Q9UQB9 Human
- Unigene: 98338 Human
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别名
- AURKC antibody
- AIE 2 antibody
- Aie1 antibody
see all
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab46783 被引用在 1 文献中.
- Chen L et al. BRDT promotes ovarian cancer cell growth. Cell Death Dis 11:1021 (2020). PubMed: 33257688