Anti-IPL-1/STK13/Aurora C抗体(ab99492)

概述

  • 产品名称
    Anti-IPL-1/STK13/Aurora C抗体
    参阅全部 IPL-1/STK13/Aurora C 一抗
  • 描述
    山羊多克隆抗体to IPL-1/STK13/Aurora C
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    PRAVVQLGKAQP

    by a Cysteine residue linker, corresponding to N terminal amino acids 4-15 of Human IPL-1/STK13/Aurora C (NP_001015878.1)

  • 阳性对照
    • Human testis lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab99492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 36 kDa.

靶标

  • 功能
    May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis.
  • 组织特异性
    Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase.
  • 疾病相关
    Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA.
  • 序列相似性
    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位
    Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AURKC antibody
    • AIE 2 antibody
    • Aie1 antibody
    • AIE2 antibody
    • AIK 3 antibody
    • AIK3 antibody
    • ARK 3 antibody
    • ARK-3 antibody
    • ARK3 antibody
    • Aur C antibody
    • AurC antibody
    • Aurkc antibody
    • AURKC_HUMAN antibody
    • aurora 3 antibody
    • Aurora C antibody
    • Aurora kinase C antibody
    • aurora related kinase 3 antibody
    • Aurora-related kinase 3 antibody
    • Aurora/Ipl1 related kinase 3 antibody
    • Aurora/Ipl1-related kinase 3 antibody
    • Aurora/Ipl1/Eg2 protein 2 antibody
    • EC 2.7.11.1 antibody
    • Serine threonine protein kinase 13 antibody
    • serine/threonine kinase 13 (aurora/IPL1 like) antibody
    • serine/threonine protein kinase aurora C antibody
    • Serine/threonine-protein kinase 13 antibody
    • Serine/threonine-protein kinase aurora-C antibody
    • SPGF5 antibody
    • STK13 antibody
    see all

图片

  • Anti-IPL-1/STK13/Aurora C antibody (ab99492) at 1.5 µg/ml + Human Testis lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 36 kDa

实验方案

文献

ab99492 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab99492.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册