Anti-IPL-1/STK13/Aurora C抗体(ab38298)


  • 产品名称Anti-IPL-1/STK13/Aurora C抗体
    参阅全部 IPL-1/STK13/Aurora C 一抗
  • 描述
    兔多克隆抗体to IPL-1/STK13/Aurora C
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
    不适用于: IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, selected from within amino acids 1-50 of Human IPL-1/STK13/Aurora C, (N terminal region).

  • 阳性对照
    • 293 cell lysates and HeLa cells.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab38298 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
ELISA 1/1000.
ICC/IF 1/100 - 1/500.
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis.
    • 组织特异性Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase.
    • 疾病相关Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA.
    • 序列相似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
      Contains 1 protein kinase domain.
    • 细胞定位Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AURKC antibody
      • AIE 2 antibody
      • Aie1 antibody
      • AIE2 antibody
      • AIK 3 antibody
      • AIK3 antibody
      • ARK 3 antibody
      • ARK-3 antibody
      • ARK3 antibody
      • Aur C antibody
      • AurC antibody
      • Aurkc antibody
      • AURKC_HUMAN antibody
      • aurora 3 antibody
      • Aurora C antibody
      • Aurora kinase C antibody
      • aurora related kinase 3 antibody
      • Aurora-related kinase 3 antibody
      • Aurora/Ipl1 related kinase 3 antibody
      • Aurora/Ipl1-related kinase 3 antibody
      • Aurora/Ipl1/Eg2 protein 2 antibody
      • EC antibody
      • Serine threonine protein kinase 13 antibody
      • serine/threonine kinase 13 (aurora/IPL1 like) antibody
      • serine/threonine protein kinase aurora C antibody
      • Serine/threonine-protein kinase 13 antibody
      • Serine/threonine-protein kinase aurora-C antibody
      • SPGF5 antibody
      • STK13 antibody
      see all

    Anti-IPL-1/STK13/Aurora C antibody 图像

    • All lanes : Anti-IPL-1/STK13/Aurora C antibody (ab38298) at 1/100 dilution

      Lane 1 : 293 cell lysate expressing Flag tag
      Lane 2 : 293 cell lysate expressing Flag tagged Aurora A
      Lane 3 : 293 cell lysate expressing Flag tagged Aurora B
      Lane 4 : 293 cell lysate expressing Flag tagged Aurora C

      Predicted band size : 36 kDa
      Observed band size : 36 kDa
      Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

      This image is courtesy of Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).

    • ICC/IF image of ab38298 at 1/100 dilution staining HeLa cells, expressing GFP-Aurora C, at different cellular mitotic stages.  The images show (A), the primary antibody (B), GFP fluorescence (C), DAPI nuclear staining and (D) ab38298 merged to DAPI staining.

    Anti-IPL-1/STK13/Aurora C antibody (ab38298)参考文献

    ab38298 has not yet been referenced specifically in any publications.

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