Anti-IPL-1/STK13/Aurora C抗体(ab38297)

概述

  • 产品名称
    Anti-IPL-1/STK13/Aurora C抗体
    参阅全部 IPL-1/STK13/Aurora C 一抗
  • 描述
    兔多克隆抗体to IPL-1/STK13/Aurora C
  • 经测试应用
    适用于: WBmore details
    不适用于: ICC/IF
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human IPL-1/STK13/Aurora C aa 115-145 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q9UQB9

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab38297 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
  • 应用说明
    Is unsuitable for ICC/IF.
  • 靶标

    • 功能
      May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. May also contribute to the regulation of chromosome segregation and cytokinesis.
    • 组织特异性
      Isoform 1 and isoform 2 are expressed in testis. Elevated expression levels were seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Expression is maximum at M phase.
    • 疾病相关
      Defects in AURKC are the cause of male infertility with large-headed multiflagellar polyploid spermatozoa (MIMPS) [MIM:243060]; also known as infertility associated with multi-tailed spermatozoa and excessive DNA.
    • 序列相似性
      Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
      Contains 1 protein kinase domain.
    • 细胞定位
      Chromosome. Cytoplasm > cytoskeleton > spindle. Distributes in the condensed chromosomes during prophase to metaphase. After entering anaphase, there is a dissociation from separated chromosomes and a redistribution to midzone microtubules, and finally remaines in the midbody during cytokinesis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AURKC antibody
      • AIE 2 antibody
      • Aie1 antibody
      • AIE2 antibody
      • AIK 3 antibody
      • AIK3 antibody
      • ARK 3 antibody
      • ARK-3 antibody
      • ARK3 antibody
      • Aur C antibody
      • AurC antibody
      • Aurkc antibody
      • AURKC_HUMAN antibody
      • aurora 3 antibody
      • Aurora C antibody
      • Aurora kinase C antibody
      • aurora related kinase 3 antibody
      • Aurora-related kinase 3 antibody
      • Aurora/Ipl1 related kinase 3 antibody
      • Aurora/Ipl1-related kinase 3 antibody
      • Aurora/Ipl1/Eg2 protein 2 antibody
      • EC 2.7.11.1 antibody
      • Serine threonine protein kinase 13 antibody
      • serine/threonine kinase 13 (aurora/IPL1 like) antibody
      • serine/threonine protein kinase aurora C antibody
      • Serine/threonine-protein kinase 13 antibody
      • Serine/threonine-protein kinase aurora-C antibody
      • SPGF5 antibody
      • STK13 antibody
      see all

    图片

    • All lanes : Anti-IPL-1/STK13/Aurora C antibody (ab38297)

      Lane 1 : 293 cell lysate expressing Flag tag
      Lane 2 : 293 cell lysate expressing Flag tagged Aurora A
      Lane 3 : 293 cell lysate expressing Flag tagged Aurora B
      Lane 4 : 293 cell lysate expressing Flag tagged Aurora C


      Predicted band size : 36 kDa
      Observed band size : 36 kDa
      Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

      This image is courtesy of Drs. K. Sasai and S. Sen from the University of Texas MD Anderson Cancer Center (Houston, TX).

    • Anti-IPL-1/STK13/Aurora C antibody (ab38297) + 293 cell lysate at 35 µg

      Predicted band size : 36 kDa

    实验方案

    文献

    ab38297 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Application
    Immunocytochemistry/ Immunofluorescence
    Sample
    Human Cell (HeLa)
    Specification
    HeLa
    Fixative
    Paraformaldehyde
    Username

    Dr. Kirk Mcmanus

    Verified customer

    提交于 Mar 19 2007

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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