概述

  • 产品名称
    Anti-IP6 Kinase抗体
  • 描述
    兔多克隆抗体to IP6 Kinase
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Mouse, Rabbit, Cow, Human
  • 免疫原

    Synthetic peptide corresponding to Human IP6 Kinase aa 216-233.
    Sequence:

    PCVLDLKMGTRQHGDDAS


    (Peptide available as ab5007)

  • 阳性对照
    • WB: rat brain extract.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.05% Sodium azide
    Constituents: 0.1% BSA, 99% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • Primary antibody说明
    Inositol 1,4,5-trisphosphate (IP3) is a second messenger for many growth factors, hormones, and neurotransmitters and, upon binding to the IP3 receptor (IP3R), triggers the release of intracellular, luminal calcium to the cytosol. Several additional cellular forms of inositol phosphates have been discovered. These include some which have been recently discovered and characterized to possess up to seven or eight phosphate groups, including pyrophosphates (PP-IPs: pyrophosphate-inositol phosphates). It has been proposed that high-energy pyrophosphates may participate in protein phosphorylation. Inositol Hexakisphosphate (IP6) Kinase, or PiUS (Pi Uptake Stimulator) has ATP synthase activity and transfers a phosphate from PP-IP5 to ADP to form ATP thus suggesting an important physiological role for PP-IP5 and IP6 kinase.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab3524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 46 kDa).Can be blocked with IP6 Kinase peptide (ab5007).

This antibody detects an ~50 kDa protein representing IP6 kinase from rat brain extract.

靶标

  • 相关性
    Inositol phosphokinase (IPK) family are responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.
  • 细胞定位
    Cytoplasmic
  • 数据库链接
  • 别名
    • ATP:1D myo inositol hexakisphosphate phosphotransferase antibody
    • IHPK3 antibody
    • Inositol hexakisphosphate kinase 3 antibody
    • Inositol hexaphosphate kinase 3 antibody
    • InsP6 kinase 3 antibody
    • INSP6K3 antibody
    • IP6K3 antibody
    • IP6K3_HUMAN antibody
    see all

Anti-IP6 Kinase antibody 图像



  • Predicted band size : 46 kDa

    Western blot detection of IP6 kinase on rat brain extract using ab3524.

     

实验方案

Anti-IP6 Kinase antibody (ab3524)参考文献

ab3524 has not yet been referenced specifically in any publications.

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