概述

  • 产品名称Anti-IP3KC抗体
    参阅全部 IP3KC 一抗
  • 描述
    山羊多克隆抗体to IP3KC
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    ETERPKQKTEPDRSS

    , corresponding to internal sequence amino acids 105-119 of Human IP3KC (NP_079470.1)

  • 阳性对照
    • Human Pancreas lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab92283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 75 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
    • 组织特异性Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
    • 疾病相关Defects in ITPKC are a cause of Kawasaki disease (KWD) [MIM:611775]; also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self-limited vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries.
    • 序列相似性Belongs to the inositol phosphokinase (IPK) family.
    • 细胞定位Nucleus. Cytoplasm. Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 4 antibody
      • 5-trisphosphate 3-kinase C antibody
      • Inositol 1 antibody
      • inositol 1,4,5 trisphosphate 3 kinase C antibody
      • Inositol trisphosphate 3 kinase C antibody
      • Inositol-trisphosphate 3-kinase C antibody
      • InsP 3 kinase C antibody
      • InsP 3-kinase C antibody
      • IP3 3-kinase C antibody
      • IP3 3KC antibody
      • IP3K C antibody
      • IP3KC antibody
      • IP3KC_HUMAN antibody
      • Itpkc antibody
      see all

    Anti-IP3KC antibody 图像

    • Anti-IP3KC antibody (ab92283) at 1 µg/ml + Human Pancreas lysate at 35 µg
      Developed using the ECL technique

      Predicted band size : 75 kDa
      Observed band size : 75 kDa

    Anti-IP3KC antibody (ab92283)参考文献

    ab92283 has not yet been referenced specifically in any publications.

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