Anti-Ionotropic glutamate receptor 2 + 3抗体(ab27225)

概述

  • 产品名称Anti-Ionotropic glutamate receptor 2 + 3抗体
    参阅全部 Ionotropic glutamate receptor 2 + 3 一抗
  • 描述
    兔多克隆抗体to Ionotropic glutamate receptor 2 + 3
  • 经测试应用适用于: IHC-FoFr, WB, IP, IHC-Pmore details
  • 种属反应性
    与反应: Pigeon, Human
    预测可用于: Mouse, Rat, Bird, Monkey
  • 免疫原

    A synthetic peptide from C terminus of Human GluR2/3.

  • 阳性对照
    • Cerebellum

性能

应用

Our Abpromise guarantee covers the use of ab27225 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-FoFr Use at an assay dependent concentration. PubMed: 20674673
WB Use at an assay dependent concentration. Predicted molecular weight: 96 kDa.
IP Use at an assay dependent concentration.
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 相关性Ion channels activated by glutamate are typically divided into two classes. Those sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). AMPAR are comprised of four distinct Glutamate Receptor Subunits (GluR1-4) and they play key roles in almost all excitatory neurotransmission in the brain. The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory.
  • 细胞定位Cell Membrane; multi-pass membrane protein.
  • 数据库链接
  • 别名
    • AMPA selective glutamate receptor 2 antibody
    • AMPA selective glutamate receptor 3 antibody
    • GluR K2 antibody
    • GluR K3 antibody
    • GLURB antibody
    • GLURC antibody
    • GLUTAMATE RECEPTOR 2 antibody
    • GLUTAMATE RECEPTOR 3 antibody
    • Glutamate receptor ionotropic AMPA 2 antibody
    • Glutamate receptor ionotropic AMPA 3 antibody
    • GRIA2 antibody
    • GRIA3 antibody
    see all

Anti-Ionotropic glutamate receptor 2 + 3 antibody 图像

  • Ab27225 at a dilution of 1/50, staining ionotropic Glutamate Receptor 2+3 in Human cerebellum by Immunohistochemistry (formalin fixed, paraffin embedded sections).

Anti-Ionotropic glutamate receptor 2 + 3 antibody (ab27225)参考文献

This product has been referenced in:
  • Ripka S  et al. Glutamate receptor GRIA3--target of CUX1 and mediator of tumor progression in pancreatic cancer. Neoplasia 12:659-67 (2010). IHC-P ; Human . Read more (PubMed: 20689760) »
  • Cabral AL  et al. GluR2/3 label expression of the AMPA-type glutamate receptor in the hippocampal formation of the homing pigeon stabilizes just after birth. Neurosci Lett 483:73-7 (2010). WB, IHC-FoFr ; Pigeon . Read more (PubMed: 20674673) »

See all 2 Publications for this product

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