Anti-Interferon regulatory factor 9抗体(ab56677)

概述

性能

应用

Our Abpromise guarantee covers the use of ab56677 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 44 kDa.
IHC-P Use a concentration of 3 µg/ml.

靶标

  • 功能Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
  • 序列相似性Belongs to the IRF family.
    Contains 1 IRF tryptophan pentad repeat DNA-binding domain.
  • 细胞定位Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IFN alpha responsive transcription factor subunit antibody
    • IFN-alpha-responsive transcription factor subunit antibody
    • Interferon regulatory factor 9 antibody
    • interferon stimulated transcription factor 3 antibody
    • Interferon-stimulated gene factor 3 gamma antibody
    • interferon-stimulated transcription factor 3, gamma 48kDa antibody
    • IRF 9 antibody
    • IRF-9 antibody
    • Irf9 antibody
    • IRF9_HUMAN antibody
    • ISGF 3 gamma antibody
    • ISGF-3 gamma antibody
    • ISGF3 antibody
    • ISGF3 p48 subunit antibody
    • ISGF3G antibody
    • OTTHUMP00000164692 antibody
    • OTTHUMP00000164693 antibody
    • p48 antibody
    • Transcriptional regulator ISGF3 subunit gamma antibody
    see all

Anti-Interferon regulatory factor 9 antibody 图像

  • TF IRF9 antibody (ab56677) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human malignant lymphoma, diffuse large B tissue.
  • Anti-Interferon regulatory factor 9 antibody (ab56677) at 1 µg/ml + MCF7 cell lysate at 25 µg

    Predicted band size : 44 kDa

Anti-Interferon regulatory factor 9 antibody (ab56677)参考文献

ab56677 has not yet been referenced specifically in any publications.

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