Anti-Interferon gamma抗体[GIF-7] (ab9808)

概述

  • 产品名称Anti-Interferon gamma抗体[GIF-7]
    参阅全部 Interferon gamma 一抗
  • 描述
    小鼠单克隆抗体[GIF-7] to Interferon gamma
  • 特异性Recognizes human IFN-g. Does not react with human IFN-a.
  • 经测试应用适用于: ELISA, Indirect ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human).

性能

应用

Our Abpromise guarantee covers the use of ab9808 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
Indirect ELISA
WB
  • 应用说明Indirect ELISA: use at 1/1000 to 1/5000
    Western Blot: use at 1/500 to 1/2000

  • 靶标

    • 功能Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
    • 组织特异性Released primarily from activated T lymphocytes.
    • 疾病相关In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
    • 序列相似性Belongs to the type II (or gamma) interferon family.
    • 翻译后修饰Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • IFG antibody
      • IFI antibody
      • IFN gamma antibody
      • IFN, immune antibody
      • IFN-gamma antibody
      • IFNG antibody
      • IFNG_HUMAN antibody
      • Immune interferon antibody
      • Interferon gamma antibody
      see all

    Anti-Interferon gamma antibody [GIF-7] 图像

    • Western blot against human interferon gamma using ab9808 at 1 µg/ml.

    Anti-Interferon gamma antibody [GIF-7] (ab9808)参考文献

    ab9808 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry. We do not have a Western blot image with molecular weight markers for this antibody. Interferon gamma precursor is 19 kD and can be expected to run on an SDS-PAGE gel at 17 - 20 kD. The Western blot band may appear broad...

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    Thank you for your enquiry. Regarding the Western blot for ab9808: Protein (interferon-gamma) loading was 200 ng per lane. Ab9808 was used at a concentration of 1 microgram/ml. Secondary antibody: anti-mouse IgG, HRP-labeled, 1:1000 Substrate: ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"