Anti-Interferon gamma抗体[A151D5B8] (ab24968)

概述

  • 产品名称Anti-Interferon gamma抗体[A151D5B8]
    参阅全部 Interferon gamma 一抗
  • 描述
    小鼠单克隆抗体[A151D5B8] to Interferon gamma
  • 特异性ab24968 recognises natural and recombinant Interferon gamma.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Pig
  • 免疫原

    Recombinant porcine interferon gamma.

性能

应用

Our Abpromise guarantee covers the use of ab24968 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
  • 应用说明ELISA: Use at a concentration of 1 - 5 µg/ml.
    Note: This antibody is suitable for use in ELISA as a coating antibody. Immediately prior to use as a coating antibody in ELISA, dilute this preparation to a final concentration of 1 - 5 µg/mL, and use 100 µL to coat each well of a microtiter plate.
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
    • 组织特异性Released primarily from activated T lymphocytes.
    • 疾病相关In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
    • 序列相似性Belongs to the type II (or gamma) interferon family.
    • 翻译后修饰Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • IFG antibody
      • IFI antibody
      • IFN gamma antibody
      • IFN, immune antibody
      • IFN-gamma antibody
      • IFNG antibody
      • IFNG_HUMAN antibody
      • Immune interferon antibody
      • Interferon gamma antibody
      see all

    Anti-Interferon gamma antibody [A151D5B8] (ab24968)参考文献

    This product has been referenced in:
    • Lee J  et al. Gammadelta T cells in immunity induced by Mycobacterium bovis bacillus Calmette-Guérin vaccination. Infect Immun 72:1504-11 (2004). Read more (PubMed: 14977956) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"