Anti-Integrin linked ILK抗体(ab55292)


  • 产品名称Anti-Integrin linked ILK抗体
    参阅全部 Integrin linked ILK 一抗
  • 描述
    小鼠单克隆抗体to Integrin linked ILK
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment (GST-tag) corresponding to Human Integrin linked ILK aa 341-453.



  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域


Our Abpromise guarantee covers the use of ab55292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 51 kDa.
ICC/IF Use at an assay dependent concentration.


  • 功能Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
  • 组织特异性Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
  • 序列相似性Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
    Contains 5 ANK repeats.
    Contains 1 protein kinase domain.
  • 结构域A PH-like domain is involved in phosphatidylinositol phosphate binding.
  • 翻译后修饰Autophosphorylated on serine residues.
  • 细胞定位Cell junction > focal adhesion. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 59 kDa serine/threonine protein kinase antibody
    • 59 kDa serine/threonine-protein kinase antibody
    • DKFZp686F1765 antibody
    • Epididymis secretory protein Li 28 antibody
    • HEL S 28 antibody
    • ILK 1 antibody
    • ILK 2 antibody
    • ILK antibody
    • ILK-1 antibody
    • ILK-2 antibody
    • ILK_HUMAN antibody
    • ILK1 antibody
    • ILK2 antibody
    • Integrin linked kinase 2 antibody
    • Integrin linked Kinase antibody
    • Integrin linked protein kinase antibody
    • Integrin-linked protein kinase antibody
    • p59 antibody
    • p59ILK antibody
    see all

Anti-Integrin linked ILK antibody 图像

  • Predicted band size : 51 kDa

    Western blot analysis of ILK over-expressed 293 cell line, cotransfected with ILK Validated Chimera RNAi  (Lane 2) or non-transfected control (Lane 1). Blot probed with ILK monoclonal antibody  (ab55292 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

  • Immunofluorescence of Jurkat cells using ab55292 dilute to 10 μg/ml to stain ILK.

  • Anti-Integrin linked ILK antibody (ab55292) + NIH/3T3 Cell lysate

    Predicted band size : 51 kDa
  • Anti-Integrin linked ILK antibody (ab55292) + RAW 264.7 Cell Lysate

    Predicted band size : 51 kDa
  • Anti-Integrin linked ILK antibody (ab55292) + HepG2 Lysate

    Predicted band size : 51 kDa
  • Anti-Integrin linked ILK antibody (ab55292) + PC-12 Lysate

    Predicted band size : 51 kDa

  • Predicted band size : 51 kDa
    Integrin linked ILK antibody (ab55292) at 1ug/lane + HeLa cell lysate at 25ug/lane.

Anti-Integrin linked ILK antibody (ab55292)参考文献

ab55292 has not yet been referenced specifically in any publications.

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