Anti-Integrin beta 4抗体[346-11A] (Biotin) (ab54414)


  • 产品名称Anti-Integrin beta 4抗体[346-11A] (Biotin)
    参阅全部 Integrin beta 4 一抗
  • 描述
    大鼠单克隆抗体[346-11A] to Integrin beta 4 (Biotin)
  • 偶联物Biotin
  • 特异性This antibody is specific to mouse CD104
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Tumour Surface Protein-180 purified from Balb/c murine carcinoma.

  • 阳性对照
    • Mouse thymocytes
  • 常规说明Shelf Life - 18 months, product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明Purified from tissue culture supernatant
  • 克隆单克隆
  • 克隆编号346-11A
  • 骨髓瘤P3-x63-Ag8
  • 同种型IgG2a
  • 研究领域


Our Abpromise guarantee covers the use of ab54414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use neat or to a 1/5 dilution. Use 10µl of the suggested working dilution to label 106 cells in 100µl

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells.
    • 组织特异性Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.
    • 疾病相关Defects in ITGB4 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA) [MIM:226730]; also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is an autosomal recessive, frequently lethal, epidermolysis bullosa with variable involvement of skin, nails, mucosa, and with variable effects on the digestive system. It is characterized by mucocutaneous fragility, aplasia cutis congenita, and gastrointestinal atresia, which most commonly affects the pylorus. Pyloric atresia is a primary manifestation rather than a scarring process secondary to epidermolysis bullosa.
      Defects in ITGB4 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB) [MIM:226650]. GABEB is a non-lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities.
    • 序列相似性Belongs to the integrin beta chain family.
      Contains 1 Calx-beta domain.
      Contains 4 fibronectin type-III domains.
      Contains 1 PSI domain.
      Contains 1 VWFA domain.
    • 结构域The fibronectin type-III-like domains bind BPAG1 and plectin and probably also recruit BP230.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD 104 antibody
      • CD104 antibody
      • CD104 antigen antibody
      • gp150 antibody
      • Integrin beta 4 subunit antibody
      • Integrin beta-4 antibody
      • ITB4_HUMAN antibody
      • ITG B4 antibody
      • ITGB 4 antibody
      • Itgb4 antibody
      see all

    Anti-Integrin beta 4 antibody [346-11A] (Biotin) 图像

    • ab54414, used neat, staining mouse thymocytes using Flow Cytometry

    Anti-Integrin beta 4 antibody [346-11A] (Biotin) (ab54414)参考文献

    ab54414 has not yet been referenced specifically in any publications.

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