Anti-Integrin alpha V抗体(ab94704)

概述

  • 产品名称Anti-Integrin alpha V抗体
    参阅全部 Integrin alpha V 一抗
  • 描述
    兔多克隆抗体to Integrin alpha V
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Sheep, Cow, Pig
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Integrin alpha V.

    (Peptide available as ab94839.)

  • 阳性对照
    • This antibody gave a positive signal in HUVEC whole cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab94704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 130 & 148 kDa (predicted molecular weight: 116 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • antigen identified by monoclonal antibody L230 antibody
      • CD 51 antibody
      • CD51 antibody
      • DKFZp686A08142 antibody
      • integrin alpha V beta 3 antibody
      • integrin alpha-V antibody
      • Integrin alpha-V light chain antibody
      • integrin alphaVbeta3 antibody
      • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
      • ITAV_HUMAN antibody
      • ITGAV antibody
      • MSK 8 antibody
      • Msk8 antibody
      • Vitronectin receptor subunit alpha antibody
      • VNRA antibody
      • VTNR antibody
      see all

    Anti-Integrin alpha V antibody 图像

    • Anti-Integrin alpha V antibody (ab94704) at 1 µg/ml + HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell Lysate at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 116 kDa
      Observed band size : 130 + 148 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 25 kDa,58 kDa,62 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 10 minutes

    Anti-Integrin alpha V antibody (ab94704)参考文献

    ab94704 has not yet been referenced specifically in any publications.

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