Anti-Integrin alpha V抗体(ab112487)

概述

  • 产品名称Anti-Integrin alpha V抗体
    参阅全部 Integrin alpha V 一抗
  • 描述
    兔多克隆抗体to Integrin alpha V
  • 经测试应用适用于: WB, IHC-P, ICCmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to Human Integrin alpha V (C terminal).

性能

应用

Our Abpromise guarantee covers the use of ab112487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 116 kDa.
IHC-P Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC Use a concentration of 1 µg/ml.

靶标

  • 功能The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
  • 序列相似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • antigen identified by monoclonal antibody L230 antibody
    • CD 51 antibody
    • CD51 antibody
    • DKFZp686A08142 antibody
    • integrin alpha V beta 3 antibody
    • integrin alpha-V antibody
    • Integrin alpha-V light chain antibody
    • integrin alphaVbeta3 antibody
    • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
    • ITAV_HUMAN antibody
    • ITGAV antibody
    • MSK 8 antibody
    • Msk8 antibody
    • Vitronectin receptor subunit alpha antibody
    • VNRA antibody
    • VTNR antibody
    see all

Anti-Integrin alpha V antibody 图像

  • All lanes : Anti-Integrin alpha V antibody (ab112487)

    Lane 1 : Rat spleen tissue lysate
    Lane 2 : Rat pancreas tissue lysate
    Lane 3 : Rat brain tissue lysate
    Lane 4 : Rat liver tissue lysate
    Lane 5 : MM231 whole cell lysate
    Lane 6 : HeLa whole cell lysate
    Lane 7 : CEM whole cell lysate
    Lane 8 : Colo320 whole cell lysate


    Predicted band size : 116 kDa
    Observed band size : 116 kDa
  • ab112493 staining CD51 in breast cancer by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection by ABC/DAB staining.

Anti-Integrin alpha V antibody (ab112487)参考文献

ab112487 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Human Cell lysate - whole cell (Glioma)
Gel Running Conditions Reduced Denaturing (10% gel)
Loading amount 25 µg
Specification Glioma
Blocking step Milk as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

提交于 May 11 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"