Anti-Integrin alpha V抗体[13C2] (ab78613)

概述

  • 产品名称Anti-Integrin alpha V抗体[13C2]
    参阅全部 Integrin alpha V 一抗
  • 描述
    小鼠单克隆抗体[13C2] to Integrin alpha V
  • 特异性ab78613 reacts with Integrin alpha V found in osteoclasts, placenta and melanoma cell lines, some endothelial cells, smooth muscle cells and fibroblasts, and weakly in platelets.
  • 经测试应用适用于: IHC-Fr, Flow Cyt, Purificationmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human osteoclastoma tissue

  • 阳性对照
    • Human tonsil.

性能

应用

Our Abpromise guarantee covers the use of ab78613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
Flow Cyt
Purification
  • 应用说明Flow Cyt: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    P: Use at an assay dependent dilution. ab78613 can be used for purification of the vitronectin receptor.

    Note: ab78613 can be used for the following studies:
    Bone resorption modulation
    Osteoclast identification
    Malignant melanoma identification (and possible treatment)


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • antigen identified by monoclonal antibody L230 antibody
      • CD 51 antibody
      • CD51 antibody
      • DKFZp686A08142 antibody
      • integrin alpha V beta 3 antibody
      • integrin alpha-V antibody
      • Integrin alpha-V light chain antibody
      • integrin alphaVbeta3 antibody
      • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
      • ITAV_HUMAN antibody
      • ITGAV antibody
      • MSK 8 antibody
      • Msk8 antibody
      • Vitronectin receptor subunit alpha antibody
      • VNRA antibody
      • VTNR antibody
      see all

    Anti-Integrin alpha V antibody [13C2] 图像

    • ab78613 staining Integrin alpha V in blood vessel endothelium in frozen section of human tonsil.

    Anti-Integrin alpha V antibody [13C2] (ab78613)参考文献

    ab78613 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab78613.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"