兔单克隆抗体[EPR4166] to Integrin alpha E
A synthetic peptide corresponding to the extracellular domain and light chain region of Human Integrin alpha E.
HuT-78, Jurkat, 431, HeLa and K562 cell lysates.
This product is a recombinant rabbit monoclonal antibody.
A trial size is available to purchase for this antibody.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Clone EPR4166 is different from clone EPR4166(2).
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Detects a band of approximately 150 kDa (predicted molecular weight: 130 kDa).
Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. Contains 1 VWFA domain.
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Information by UniProt
Western blot - Integrin alpha E antibody [EPR4166] (ab108503)
All lanes :
Anti-Integrin alpha E antibody [EPR4166] (ab108503) at 1/1000 dilution
Lane 1 :
HuT-78 cell lysate
Lane 2 :
Jurkat cell lysate
Lane 3 :
A431 cell lysate
Lane 4 :
HeLa cell lysate
Lane 5 :
K562 cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size:
Observed band size:
150 kDa (
why is the actual band size different from the predicted?
This product has been referenced in:
et al. Multiple lesions of gastrointestinal tract invasion by monomorphic epitheliotropic intestinal T-cell lymphoma, accompanied by duodenal and intestinal enteropathy-like lesions and microscopic lymphocytic proctocolitis: a case series. Diagn Pathol 11:66 (2016).
Read more (PubMed: 27457239) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"