概述
- 产品名称Anti-Integrin alpha E抗体[AP-MAB0828]
参阅全部 Integrin alpha E 一抗 - 描述大鼠单克隆抗体[AP-MAB0828] to Integrin alpha E
- 经测试应用适用于: IP, IHC-Fr, Flow Cyt, Inhibition Assaymore details
- 种属反应性与反应: Mouse
- 免疫原
Mouse mammary tumor cells
- 常规说明
This monoclonal can be used for the inhibition of CD103 mediated adhesion.
性能
- 形式Lyophilised
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- 存储溶液Preservative: None
Constituents: PBS -
Concentration information loading... - 纯化说明The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate buffered saline.
- Primary antibody说明This monoclonal can be used for the inhibition of CD103 mediated adhesion.
- 克隆单克隆
- 克隆编号AP-MAB0828
- 同种型IgG2
- 研究领域
相关产品
- Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab83052 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IP | Use at an assay dependent dilution. | |
| IHC-Fr | Use at an assay dependent dilution. | |
| Flow Cyt | Use at an assay dependent dilution. | |
| Inhibition Assay | Use at an assay dependent dilution. |
靶标
- 功能Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
- 组织特异性Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
- 序列相似性Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. - 结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- 细胞定位Membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 16407 Mouse
- SwissProt: Q60677 Mouse
- Unigene: 96 Mouse
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别名
- A530055J10 antibody
- alpha-E1 antibody
- alpha-M290 antibody
see all
Anti-Integrin alpha E antibody [AP-MAB0828] (ab83052)参考文献
ab83052 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"