Anti-Integrin alpha E抗体[2E7] (Biotin) (ab25211)

概述

  • 产品名称Anti-Integrin alpha E抗体[2E7] (Biotin)
    参阅全部 Integrin alpha E 一抗
  • 描述
    亚美尼亚仓鼠单克隆抗体[2E7] to Integrin alpha E (Biotin)
  • 偶联物Biotin
  • 特异性ab25211 recognises CD103/aIELß7 integrin complex.
  • 经测试应用适用于: Flow Cyt, IHC-Fr, IPmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

性能

应用

Our Abpromise guarantee covers the use of ab25211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
IHC-Fr
IP
  • 应用说明Flow Cyt: Use at an assay dependent dilution. Use up to 1ug/106 cells.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    In vivo activation: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
    • 组织特异性Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • 结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A530055J10 antibody
      • alpha-E1 antibody
      • alpha-M290 antibody
      • aM290 antibody
      • Antigen CD103 antibody
      • CD 103 antibody
      • CD103 antibody
      • CD103 antigen antibody
      • HML 1 antigen antibody
      • HML-1 antigen antibody
      • HML1 antigen antibody
      • Human mucosal lymphocyte antigen 1 antibody
      • Human mucosal lymphocyte antigen 1, alpha subunit antibody
      • Huminae antibody
      • Integrin alpha E heavy chain antibody
      • Integrin alpha E light chain antibody
      • Integrin alpha E, epithelial-associated antibody
      • Integrin alpha E1 antibody
      • Integrin alpha IEL antibody
      • Integrin alpha M290 antibody
      • Integrin alpha-E heavy chain antibody
      • Integrin alpha-IEL antibody
      • Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) antibody
      • Integrin, alpha E antibody
      • ITAE_HUMAN antibody
      • Itgae antibody
      • MGC141996 antibody
      • MGC183601 antibody
      • Mucosal lymphocyte 1 antigen antibody
      • Mucosal lymphocyte antigen 1 antibody
      see all

    Anti-Integrin alpha E antibody [2E7] (Biotin) 图像

    • BALB/c mesenteric lymph node cells were first labeled with ab25211 at 0.1 µg/106 cells, and then double-stained with streptavidin-FITC and rat anti-mouse CD8a-R-PE (ab25498).  Small lymphocytes were gated and analyzed on a FACScan flow cytometer  (BDIS, San Jose, CA). 

    Anti-Integrin alpha E antibody [2E7] (Biotin) (ab25211)参考文献

    This product has been referenced in:
    • Lefrançois L  et al. Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. Eur J Immunol 24:635-40 (1994). Read more (PubMed: 7907296) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"