Anti-Integrin alpha 5抗体(ab72663)


  • 产品名称Anti-Integrin alpha 5抗体
    参阅全部 Integrin alpha 5 一抗
  • 描述
    兔多克隆抗体to Integrin alpha 5
  • 特异性ab72663 detects endogenous levels of fragment of activated Integrin alpha 5 resulting from cleavage adjacent to Phe42.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide derived from human Integrin alpha 5.

  • 阳性对照
    • Extracts from 3T3 cells treated with etoposide (25uM, 24hours).



Our Abpromise guarantee covers the use of ab72663 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 95 kDa (predicted molecular weight: 115 kDa).
ELISA 1/10000.


  • 功能Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
  • 序列相似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD49 antigen-like family member E antibody
    • CD49e antibody
    • Fibronectin receptor subunit alpha antibody
    • Fibronectin receptor, alpha subunit antibody
    • FNRA antibody
    • Integrin alpha 5 (fibronectin receptor alpha) antibody
    • Integrin alpha-5 antibody
    • Integrin alpha-5 light chain antibody
    • Integrin alpha-F antibody
    • Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody
    • ITA5_HUMAN antibody
    • Itga5 antibody
    • Very late activation protein 5, alpha subunit antibody
    • VLA-5 antibody
    • VLA5 antibody
    • VLA5A antibody
    see all

Anti-Integrin alpha 5 antibody 图像

  • All lanes : Anti-Integrin alpha 5 antibody (ab72663) at 1/500 dilution

    Lane 1 : Extracts from 3T3 cells, treated with etoposide (25uM, 24hours)
    Lane 2 : Extracts from 3T3 cells, treated with etoposide (25uM, 24hours) with Cl-peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 115 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)

Anti-Integrin alpha 5 antibody (ab72663)参考文献

ab72663 has not yet been referenced specifically in any publications.

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Thank you for your enquiry.

I apologise for the delay in getting back to you. I have been revewing and checking the immunogen sequences of our Integrin alpha 5 antibody. Regrettably, so far I am sorry I have not found one that would match yo...

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Thank you very much for your reply. Just to be sure to avoid any misunderstanding, the ab72663 will recongize only cleaved integrin alpha 5 at the Phe42. This cleaved integrin does however correspond to the active form, as the cleavage is only to get r...

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Thank you for your inquiry. This antibody ab72663 only reacts with Integrin alpha-5 when it is cleaved between G-F at position between aa41 and aa42. It does not detect the intact protein.

1) This antibody only react with Integrin alpha-5 when it is cleaved between G-F at position between aa41 and aa42. It does not detect the intact protein. 2) We used etoposide, because etoposide activates some proteases. We do not know etoposide invove...

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