Anti-Integrin alpha 4+beta 7抗体[DATK32] (Phycoerythrin) (ab25080)

概述

  • 产品名称Anti-Integrin alpha 4+beta 7抗体[DATK32] (Phycoerythrin)
    参阅全部 Integrin alpha 4+beta 7 一抗
  • 描述
    大鼠单克隆抗体[DATK32] to Integrin alpha 4+beta 7 (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 经测试应用适用于: Flow Cyt, Blocking, IHC-Frmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Tissue/ cell preparation: AKR/Cum spontaneous T lymphoma cell line TK1 (Mouse).

  • 表位This antibody recognizes a conformational epitope on the alpha 4 beta 7 heterodimer.

性能

应用

Our Abpromise guarantee covers the use of ab25080 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
Blocking
IHC-Fr
  • 应用说明BL: Use at an assay dependent dilution.
    Flow Cyt: Use <0.1µg for 106 cells.
    IHC-Fr: Use at an assay dependent dilution.
    Induction of homotypic cellular aggregation.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.
    • 细胞定位Membrane; Single pass type I membrane protein.
    • 数据库链接
    • 别名
      • Antigen CD49D antibody
      • CD49d antibody
      • IA4 antibody
      • Integrin alpha 4 subunit antibody
      • Integrin alpha IV antibody
      • Integrin beta 7 antibody
      • Integrin beta 7 subunit antibody
      • ITGA4 antibody
      • ITGB7 antibody
      • LPAM1 antibody
      see all

    Anti-Integrin alpha 4+beta 7 antibody [DATK32] (Phycoerythrin) 图像

    • Flow cytometry analysis staining Integrin alpha 4+beta 7 in T-lymphocyte cell line TK-1 using ab25080 at a dilution of 0.1 ug/106 cells. Rat Anti-Mouse LPAM-1-PE was used as an isotype control.

    Anti-Integrin alpha 4+beta 7 antibody [DATK32] (Phycoerythrin) (ab25080)参考文献

    ab25080 has not yet been referenced specifically in any publications.

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