Anti-Integrin alpha 3a抗体[29A3] (ab8985)

概述

  • 产品名称Anti-Integrin alpha 3a抗体[29A3]
  • 描述
    小鼠单克隆抗体[29A3] to Integrin alpha 3a
  • 特异性Recognizes specifically the cytoplasmic domain of integrin subunit alpha 3A which is present in the basal cell layer in skin, glomeruli, Bowman’s capsules and distal tubuli in kidney, all vascular and capillary endothelia in brain, heart and skin, and vascular smooth muscle cells in heart.
  • 经测试应用适用于: IHC-Fr, ICC, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-RTRALYEAKRQKAEMKSQPSETERLTDDY

    conjugated to KLH.

  • 表位Cytoplasmic domain of a3A Integrin. Phospho-epitope.
  • 常规说明


    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • Primary antibody说明The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.
  • 克隆单克隆
  • 克隆编号29A3
  • 骨髓瘤Sp2/0
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab8985 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration. Recommended range is 1:100 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.
ICC Use at an assay dependent concentration.
WB 1/100 - 1/1000.

靶标

  • 相关性Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins.
  • 细胞定位Cell Membrane
  • 数据库链接
  • 别名
    • CD49C antibody
    • GAPB3 antibody
    • ITGA3 antibody
    • MSK18 antibody
    • VL3A antibody
    see all

Anti-Integrin alpha 3a antibody [29A3] 图像

  • Immunohistochemistry on frozen section of human kidney

Anti-Integrin alpha 3a antibody [29A3] (ab8985)参考文献

ab8985 has not yet been referenced specifically in any publications.

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