Anti-Integrin alpha 3a抗体[29A3] (ab8985)

概述

  • 产品名称
    Anti-Integrin alpha 3a抗体[29A3]
  • 描述
    小鼠单克隆抗体[29A3] to Integrin alpha 3a
  • 特异性
    Recognizes specifically the cytoplasmic domain of integrin subunit alpha 3A which is present in the basal cell layer in skin, glomeruli, Bowman’s capsules and distal tubuli in kidney, all vascular and capillary endothelia in brain, heart and skin, and vascular smooth muscle cells in heart.
  • 经测试应用
    适用于: IHC-Fr, ICC, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: C-RTRALYEAKRQKAEMKSQPSETERLTDDY conjugated to KLH.

  • 表位
    Cytoplasmic domain of a3A Integrin. Phospho-epitope.
  • 常规说明


    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • Primary antibody说明
    The integrins, finally, form a large family of glycosylated transmembrane proteins that act as dimers of an alpha and a beta subunit in interconnecting the cytoskeleton and the extracellular matrix.
  • 克隆
    单克隆
  • 克隆编号
    29A3
  • 骨髓瘤
    Sp2/0
  • 同种型
    IgG1
  • 轻链类型
    kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab8985 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration. Recommended range is 1:100 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.
ICC Use at an assay dependent concentration.
WB 1/100 - 1/1000.

靶标

  • 相关性
    Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins.
  • 细胞定位
    Cell Membrane
  • 数据库链接
  • 别名
    • CD49C antibody
    • GAPB3 antibody
    • ITGA3 antibody
    • MSK18 antibody
    • VL3A antibody
    see all

图片

  • Immunohistochemistry on frozen section of human kidney

文献

ab8985 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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