Anti-Integrin alpha 3抗体[VJ1/6] (Allophycocyanin) (ab91043)

概述

  • 产品名称Anti-Integrin alpha 3抗体[VJ1/6] (Allophycocyanin)
    参阅全部 Integrin alpha 3 一抗
  • 描述
    小鼠单克隆抗体[VJ1/6] to Integrin alpha 3 (Allophycocyanin)
  • 偶联物Allophycocyanin. Ex: 645nm, Em: 660nm
  • 特异性Recognizes the VLA-a3 chain of the Integrin alpha 3/CD29 (VLA-3) complex.
  • 经测试应用适用于: IHC-Fr, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Integrin alpha 3 transfected cell line.

  • 阳性对照
    • Epithelial tissue, basal renal distal tubules, anticoagulated (EDTA) blood

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, pH 7.2
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆单克隆
  • 克隆编号VJ1/6
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab91043 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent dilution.
Flow Cyt Use 20µl for 106 cells.

靶标

  • 功能Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
  • 组织特异性Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
  • 序列相似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
  • 翻译后修饰Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AA407068 antibody
    • Antigen identified by monoclonal antibody J143 antibody
    • CD49 antigen like family member C antibody
    • CD49 antigen-like family member C antibody
    • CD49c antibody
    • CD49c antigen antibody
    • FLJ34631 antibody
    • FLJ34704 antibody
    • FRP 2 antibody
    • FRP-2 antibody
    • FRP2 antibody
    • Galactoprotein B3 antibody
    • GAP B3 antibody
    • GAPB3 antibody
    • Integrin alpha 3 antibody
    • Integrin alpha-3 light chain antibody
    • Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody
    • ITA3_HUMAN antibody
    • ITGA 3 antibody
    • Itga3 antibody
    • MSK18 antibody
    • VCA 2 antibody
    • VCA2 antibody
    • Very late activation protein 3 receptor alpha 3 subunit antibody
    • VL3A antibody
    • VLA 3 alpha chain antibody
    • VLA 3 subunit alpha antibody
    • VLA-3 subunit alpha antibody
    • VLA3a antibody
    see all

Anti-Integrin alpha 3 antibody [VJ1/6] (Allophycocyanin) 图像

  • Flow cytometry analysis of Human whole blood lysate, staining Integrin alpha 3 with ab91043.

    Gating Strategy: Leukocytes

    Yellow histogram = platelets
    Red histogram = lympohcytes
    Green histogram = monocytes
    Blue histogram = neutrophils

Anti-Integrin alpha 3 antibody [VJ1/6] (Allophycocyanin) (ab91043)参考文献

ab91043 has not yet been referenced specifically in any publications.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"