Anti-Integrin alpha 3抗体[17C6] (FITC) (ab30488)

概述

  • 产品名称Anti-Integrin alpha 3抗体[17C6] (FITC)
    参阅全部 Integrin alpha 3 一抗
  • 描述
    小鼠单克隆抗体[17C6] to Integrin alpha 3 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性ab30488 recognises CD49c, a 150kD cell surface antigen which is also known as the alpha-3 integrin and as VLA-3. CD49c is expressed by most cell types including T and B lymphocytes.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Integrin alpha 3 transfected cell line

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号17C6
  • 骨髓瘤NS1
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab30488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: Use at an assay dependent dilution. Use 10µl of working dilution for 106 cells in 100ul.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
    • 组织特异性Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • 翻译后修饰Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AA407068 antibody
      • Antigen identified by monoclonal antibody J143 antibody
      • CD49 antigen like family member C antibody
      • CD49 antigen-like family member C antibody
      • CD49c antibody
      • CD49c antigen antibody
      • FLJ34631 antibody
      • FLJ34704 antibody
      • FRP 2 antibody
      • FRP-2 antibody
      • FRP2 antibody
      • Galactoprotein B3 antibody
      • GAP B3 antibody
      • GAPB3 antibody
      • Integrin alpha 3 antibody
      • Integrin alpha-3 light chain antibody
      • Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody
      • ITA3_HUMAN antibody
      • ITGA 3 antibody
      • Itga3 antibody
      • MSK18 antibody
      • VCA 2 antibody
      • VCA2 antibody
      • Very late activation protein 3 receptor alpha 3 subunit antibody
      • VL3A antibody
      • VLA 3 alpha chain antibody
      • VLA 3 subunit alpha antibody
      • VLA-3 subunit alpha antibody
      • VLA3a antibody
      see all

    Anti-Integrin alpha 3 antibody [17C6] (FITC) (ab30488)参考文献

    This product has been referenced in:
    • Ingenito EP  et al. Design and testing of biological scaffolds for delivering reparative cells to target sites in the lung. J Tissue Eng Regen Med 4:259-72 (2010). Read more (PubMed: 20020503) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"