Anti-Integrin alpha 3抗体[17C6] (FITC) (ab30488)

概述

  • 产品名称
    Anti-Integrin alpha 3抗体[17C6] (FITC)
    参阅全部 Integrin alpha 3 一抗
  • 描述
    小鼠单克隆抗体[17C6] to Integrin alpha 3 (FITC)
  • 偶联物
    FITC. Ex: 493nm, Em: 528nm
  • 特异性
    ab30488 recognises CD49c, a 150kD cell surface antigen which is also known as the alpha-3 integrin and as VLA-3. CD49c is expressed by most cell types including T and B lymphocytes.
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Integrin alpha 3 transfected cell line

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 克隆编号
    17C6
  • 骨髓瘤
    NS1
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab30488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明
    Flow Cyt: Use at an assay dependent dilution. Use 10µl of working dilution for 106 cells in 100ul.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
    • 组织特异性
      Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
    • 序列相似性
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • 翻译后修饰
      Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
    • 细胞定位
      Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AA407068 antibody
      • Antigen identified by monoclonal antibody J143 antibody
      • CD49 antigen like family member C antibody
      • CD49 antigen-like family member C antibody
      • CD49c antibody
      • CD49c antigen antibody
      • FLJ34631 antibody
      • FLJ34704 antibody
      • FRP 2 antibody
      • FRP-2 antibody
      • FRP2 antibody
      • Galactoprotein B3 antibody
      • GAP B3 antibody
      • GAPB3 antibody
      • Integrin alpha 3 antibody
      • Integrin alpha-3 light chain antibody
      • Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody
      • ITA3_HUMAN antibody
      • ITGA 3 antibody
      • Itga3 antibody
      • MSK18 antibody
      • VCA 2 antibody
      • VCA2 antibody
      • Very late activation protein 3 receptor alpha 3 subunit antibody
      • VL3A antibody
      • VLA 3 alpha chain antibody
      • VLA 3 subunit alpha antibody
      • VLA-3 subunit alpha antibody
      • VLA3a antibody
      see all

    Anti-Integrin alpha 3 antibody [17C6] (FITC) (ab30488)参考文献

    This product has been referenced in:
    • Ingenito EP  et al. Design and testing of biological scaffolds for delivering reparative cells to target sites in the lung. J Tissue Eng Regen Med 4:259-72 (2010). Read more (PubMed: 20020503) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab30488.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册