Anti-Integrin alpha 2抗体[DX5] (Allophycocyanin/Cy7 ®) (ab46795)

概述

  • 产品名称Anti-Integrin alpha 2抗体[DX5] (Allophycocyanin/Cy7 ®)
    参阅全部 Integrin alpha 2 一抗
  • 描述
    大鼠单克隆抗体[DX5] to Integrin alpha 2 (Allophycocyanin/Cy7 ®)
  • 偶联物Allophycocyanin/Cy7 ®. Ex: 650nm, Em: 774nm
  • 特异性ab46795 reacts with mouse CD49b, Mr 160-kDa.
  • 经测试应用适用于: Flow Cytmore details
    不适用于: IHC-Fr or IHC-P
  • 种属反应性
    与反应: Mouse
  • 免疫原

    RIL 2 propagated NK1.1+ cells from C57BL/6 mice. (Fusion Partner Mouse SP2/0 myeloma cell line).

  • 常规说明This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

性能

应用

Our Abpromise guarantee covers the use of ab46795 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.2µl for 106 cells.
  • 应用说明Is unsuitable for IHC-Fr or IHC-P.
  • 靶标

    • 功能Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • 结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BR antibody
      • CD 49b antibody
      • CD49 antigen like family member B antibody
      • CD49 antigen-like family member B antibody
      • CD49b antibody
      • CD49b antigen antibody
      • Collagen receptor antibody
      • DX5 antibody
      • Glycoprotein Ia deficiency included antibody
      • GP Ia antibody
      • GP Ia deficiency, included antibody
      • GPIa antibody
      • HPA 5 included antibody
      • HPA5 included antibody
      • Human platelet alloantigen system 5 antibody
      • Integrin alpha 2 antibody
      • Integrin alpha-2 antibody
      • Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody
      • ITA2_HUMAN antibody
      • ITGA2 antibody
      • Platelet alloantigen Br(a), included antibody
      • Platelet antigen Br antibody
      • Platelet glycoprotein GPIa antibody
      • Platelet glycoprotein Ia antibody
      • Platelet glycoprotein Ia/IIa antibody
      • Platelet membrane glycoprotein Ia antibody
      • Platelet receptor for collagen, deficiency of, included antibody
      • Very late activation protein 2 receptor alpha 2 subunit antibody
      • VLA 2 alpha chain antibody
      • VLA 2 antibody
      • VLA 2 subunit alpha antibody
      • VLA-2 subunit alpha antibody
      • VLA2 antibody
      • VLA2 receptor alpha 2 subunit antibody
      • VLAA2 antibody
      see all

    Anti-Integrin alpha 2 antibody [DX5] (Allophycocyanin/Cy7 ®) 图像

    • FACS analysis of B6 splenocytes, doublestained with rat anti-mouse CD49b (integrin alpha 2)-APC/Cy7 (ab46795) at 0.2 µl/106 cells and CD3-FITC.

    Anti-Integrin alpha 2 antibody [DX5] (Allophycocyanin/Cy7 ®) (ab46795)参考文献

    ab46795 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your e-mail.
    I have contacted the Lab which produce this antibody regarding your question:
    "The immunogen used to produce this antibody was RIL-2-propagated NK1.1+ cells from C57BL/6 mice, though this antibody stains the...

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    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Flow Cytometry
    Sample Mouse Cell (whole blood)
    Specification whole blood
    Permeabilization No
    Gating Strategy monocyte, lymphocyte and granulocyte
    Username

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    Verified customer

    提交于 May 01 2012

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"