Anti-Integrin alpha 2抗体[AK7] (FITC) (ab30486)

概述

  • 产品名称Anti-Integrin alpha 2抗体[AK7] (FITC)
    参阅全部 Integrin alpha 2 一抗
  • 描述
    小鼠单克隆抗体[AK7] to Integrin alpha 2 (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性ab30486 recognises the integrin alpha 2 subunit, which is a 160kD glycoprotein that non covalently associates with the 130kD integrin beta 1 subunit (CD29) to form the VLA2 complex.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human, Monkey, Baboon, Cynomolgus Monkey, Rhesus monkey
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • 常规说明

    Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC).

性能

应用

Our Abpromise guarantee covers the use of ab30486 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt
  • 应用说明Flow Cyt: 1/Neat - 1/5. Use 10µl of the working dilution for 106 cells or 100ul whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
    • 序列相似性Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • 结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BR antibody
      • CD 49b antibody
      • CD49 antigen like family member B antibody
      • CD49 antigen-like family member B antibody
      • CD49b antibody
      • CD49b antigen antibody
      • Collagen receptor antibody
      • DX5 antibody
      • Glycoprotein Ia deficiency included antibody
      • GP Ia antibody
      • GP Ia deficiency, included antibody
      • GPIa antibody
      • HPA 5 included antibody
      • HPA5 included antibody
      • Human platelet alloantigen system 5 antibody
      • Integrin alpha 2 antibody
      • Integrin alpha-2 antibody
      • Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody
      • ITA2_HUMAN antibody
      • ITGA2 antibody
      • Platelet alloantigen Br(a), included antibody
      • Platelet antigen Br antibody
      • Platelet glycoprotein GPIa antibody
      • Platelet glycoprotein Ia antibody
      • Platelet glycoprotein Ia/IIa antibody
      • Platelet membrane glycoprotein Ia antibody
      • Platelet receptor for collagen, deficiency of, included antibody
      • Very late activation protein 2 receptor alpha 2 subunit antibody
      • VLA 2 alpha chain antibody
      • VLA 2 antibody
      • VLA 2 subunit alpha antibody
      • VLA-2 subunit alpha antibody
      • VLA2 antibody
      • VLA2 receptor alpha 2 subunit antibody
      • VLAA2 antibody
      see all

    Anti-Integrin alpha 2 antibody [AK7] (FITC) 图像

    • Flow cytometric analysis of human peripheral blood platlets with 10µl for 106 cells of anti human CD49b FITC conjugated (ab30486).

    Anti-Integrin alpha 2 antibody [AK7] (FITC) (ab30486)参考文献

    This product has been referenced in:
    • Hellevik T  et al. Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced. Radiat Oncol 7:59 (2012). Flow Cyt ; Human . Read more (PubMed: 22500976) »
    • Ingenito EP  et al. Design and testing of biological scaffolds for delivering reparative cells to target sites in the lung. J Tissue Eng Regen Med 4:259-72 (2010). Read more (PubMed: 20020503) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"