Anti-Integrin alpha 1 + beta 1抗体[RA1.1] (ab79007)

概述

  • 产品名称Anti-Integrin alpha 1 + beta 1抗体[RA1.1]
  • 描述
    小鼠单克隆抗体[RA1.1] to Integrin alpha 1 + beta 1
  • 特异性Specifically binds Rat integrin alpha 1 + beta 1 (VLA-1 complex), will not recognize the individual integrin subunits. Does not inhibit VLA-1 mediated adhesion to matrix proteins.
  • 经测试应用适用于: IP, IHC-Fr, Flow Cytmore details
    不适用于: WB
  • 种属反应性
    与反应: Rat
  • 免疫原

    Rat pheochromocytoma PC12 cells.

  • 阳性对照
    • Rat gut, heart and lung tissue.

性能

应用

Our Abpromise guarantee covers the use of ab79007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP
IHC-Fr
Flow Cyt
  • 应用说明Flow Cyt: Use at a concentration of 10 µg/ml.
    IHC-Fr: Use at a concentration of 20 µg/ml. Acetone fixation recommended.
    IP from detergent cell lysates: Use 2µg for 106 cell equivalent.


    Is unsuitable for WB.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. Integrin alpha 1 heterodimerizes with Integrin beta 1 to form a cell-surface receptor for collagen and laminin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis.
    • 细胞定位Cell membrane; Single-pass type I membrane protein.
    • 数据库链接
    • 别名
      • Antigen CD29 antibody
      • CD29 antibody
      • CD29 antigen antibody
      • CD49 antigen like family member A antibody
      • CD49a antibody
      • CD49a antigen antibody
      • Fibronectin receptor beta polypeptide antibody
      • Fibronectin receptor beta subunit antibody
      • Fibronectin receptor subunit beta antibody
      • FNRB antibody
      • GPIIA antibody
      • Integrin alpha 1 antibody
      • Integrin beta 1 antibody
      • Integrin VLA 4 beta subunit antibody
      • Integrin VLA 4 subunit beta antibody
      • ITGA 1 antibody
      • ITGA1 antibody
      • ITGB 1 antibody
      • ITGB1 antibody
      • Laminin and collagen receptor antibody
      • MDF2 antibody
      • MSK12 antibody
      • Very late activation protein 1 antibody
      • VLA 1 antibody
      • VLA betA antibody
      • VLA1 antibody
      • VLAB antibody
      see all

    Anti-Integrin alpha 1 + beta 1 antibody [RA1.1] 图像

    • ab79007, at 20µg/ml, staining Integrin alpha 1 + beta 1 in rat heart tissue by immunohistochemistry using acetone fixed frozen tissue sections.
    • ab79007, at 20µg/ml, staining Integrin alpha 1 + beta 1 in rat lung tissue by immunohistochemistry using acetone fixed frozen tissue sections.

    Anti-Integrin alpha 1 + beta 1 antibody [RA1.1] (ab79007)参考文献

    ab79007 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you very much for your interest in ab79007.

    This is our only anti-VLA-1 complex antibody in our catalogue and to our knowledge it has not been tested in human. Therefore, I can offer a discount off a future purchase if you buy ab79007 ...

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    Thank you very much for contacting us - and sending the enquiry as a table. That clear overview was very helpful :-) As you may know, we have not tested the individual samples for their expression of the mentioned targets. However, according to the ...

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    Thank you very much for your interest in ab79007. To our knowledge, ab79007 has not been tested in rat. As the immunogen used was whole cells, I can not make a prediction of crossreactivity by aligning the immunogen peptide. It could be that the antibo...

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    We don't have a catalog option without sodium azide, although if you need 10 or more vias we can probably work this as a bulk customer order. The hybridoma was raised against rat pheochromocytoma PC12 cells. The antibody will not recognize the ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"