Anti-Integrin alpha 1抗体[TS2/7] (ab34445)
- 数据表
- 具体的参考文献 (1)
- 实验方案
概述
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产品名称Anti-Integrin alpha 1抗体[TS2/7]
参阅全部 Integrin alpha 1 一抗 -
描述小鼠单克隆抗体[TS2/7] to Integrin alpha 1
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特异性ab34445 recognises alpha 1 integrin subunit.
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经测试应用适用于: Flow Cyt, IHC-Fr, IPmore details
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种属反应性与反应: Human
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免疫原
Human Integrin alpha 1 subunit.
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阳性对照
- HeLa cells
性能
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形式Liquid
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存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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存储溶液Preservative: 0.09% Sodium Azide
Constituents: PBS, pH 7.4 -
Concentration information loading... -
纯度Protein G purified
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纯化说明Purified from tissue culture supernatant.
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克隆单克隆
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克隆编号TS2/7
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同种型IgG1
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研究领域
相关产品
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Compatible Secondaries
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Conjugation kits
应用
Our Abpromise guarantee covers the use of ab34445 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
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| Flow Cyt | 1/25 - 1/50. Use 10µl of the suggested working dilution to label 106 cells in 100µl.
ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
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| IHC-Fr | Use at an assay dependent concentration. | |
| IP | Use at an assay dependent concentration. |
靶标
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功能Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
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序列相似性Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
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细胞定位Membrane.
- Information by UniProt
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数据库链接
- Entrez Gene: 3672 Human
- Omim: 192968 Human
- SwissProt: P56199 Human
- Unigene: 644352 Human
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别名
- CD 49a antibody
- CD49 antigen-like family member A antibody
- CD49a antibody
see all
Anti-Integrin alpha 1 antibody [TS2/7] 图像
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![Flow Cytometry / FACS - Integrin alpha 1 antibody [TS2/7] (ab34445)](http://www.abcam.cn/ps/datasheet/Images/34/ab34445/ab34445.gif)
Flow Cytometry / FACS - Integrin alpha 1 antibody [TS2/7] (ab34445)Staining of HeLa cells with MOUSE ANTI HUMAN CD49a (ab34445).
Anti-Integrin alpha 1 antibody [TS2/7] (ab34445)参考文献
This product has been referenced in:
- Chen X et al. Integrin-mediated type II TGF-ß receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. J Clin Invest 124:3295-310 (2014). IHC-Fr, Flow Cyt ; Human . Read more (PubMed: 24983314) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"