Anti-Integrin alpha 1抗体[TS2/7] (ab34445)

概述

  • 产品名称
    Anti-Integrin alpha 1抗体[TS2/7]
    参阅全部 Integrin alpha 1 一抗
  • 描述
    小鼠单克隆抗体[TS2/7] to Integrin alpha 1
  • 特异性
    ab34445 recognises alpha 1 integrin subunit.
  • 经测试应用
    适用于: Flow Cyt, IHC-Fr, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human Integrin alpha 1 subunit.

  • 阳性对照
    • HeLa cells

性能

应用

Our Abpromise guarantee covers the use of ab34445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/25 - 1/50. Use 10µl of the suggested working dilution to label 106 cells in 100µl.



ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

靶标

  • 功能
    Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
  • 序列相似性
    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • 结构域
    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 49a antibody
    • CD49 antigen-like family member A antibody
    • CD49a antibody
    • CD49a antigen antibody
    • Integrin alpha-1 antibody
    • ITA1_HUMAN antibody
    • Itga 1 antibody
    • ITGA1 antibody
    • Laminin and collagen receptor antibody
    • Very late activation protein 1 antibody
    • VLA 1 antibody
    • VLA-1 antibody
    • VLA1 antibody
    see all

图片

  • Staining of HeLa cells with MOUSE ANTI HUMAN CD49a (ab34445).

文献

This product has been referenced in:
  • Verma R  et al. Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. PLoS One 11:e0148906 (2016). Read more (PubMed: 26848974) »
  • Al Thawadi H  et al. VE-cadherin cleavage by ovarian cancer microparticles induces ß-catenin phosphorylation in endothelial cells. Oncotarget 7:5289-305 (2016). WB . Read more (PubMed: 26700621) »

See all 3 Publications for this product

客户评价及客户问答

Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (Tumour Cells)
Specification
Tumour Cells
Fixative
Paraformaldehyde
Permeabilization
No
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: RT°C
Username

Dr. Sharon Sneddon

Verified customer

提交于 Jul 11 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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