Anti-Integrin alpha 1抗体[TS2/7] (ab34445)

Abreviews (1) Submit a Question Specific References (3)

概述

  • 产品名称
    Anti-Integrin alpha 1抗体[TS2/7]
    参阅全部 Integrin alpha 1 一抗
  • 描述
    小鼠单克隆抗体[TS2/7] to Integrin alpha 1
  • 宿主
    Mouse
  • 特异性
    ab34445 recognises alpha 1 integrin subunit.
  • 经测试应用
    适用于: Flow Cyt, IHC-Fr, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human Integrin alpha 1 subunit.

  • 阳性对照
    • HeLa cells

性能

应用

Our Abpromise guarantee covers the use of ab34445 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/25 - 1/50.

Use 10µl of the suggested working dilution to label 106 cells in 100µl.

 

 

 

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 
IHC-Fr Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

靶标

  • 功能
    Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
  • 序列相似性
    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • 结构域
    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
    • 别名
      • CD 49a antibody
      • CD49 antigen-like family member A antibody
      • CD49a antibody
      • CD49a antigen antibody
      • Integrin alpha-1 antibody
      • ITA1_HUMAN antibody
      • Itga 1 antibody
      • ITGA1 antibody
      • Laminin and collagen receptor antibody
      • Very late activation protein 1 antibody
      • VLA 1 antibody
      • VLA-1 antibody
      • VLA1 antibody
      see all

    图片

    • Flow Cytometry - Anti-Integrin alpha 1 antibody [TS2/7] (ab34445)
      Flow Cytometry - Anti-Integrin alpha 1 antibody [TS2/7] (ab34445)
      Staining of HeLa cells with MOUSE ANTI HUMAN CD49a (ab34445).

    文献

    This product has been referenced in:
    • Verma R  et al. Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. PLoS One 11:e0148906 (2016). Read more (PubMed: 26848974) »
    • Al Thawadi H  et al. VE-cadherin cleavage by ovarian cancer microparticles induces ß-catenin phosphorylation in endothelial cells. Oncotarget 7:5289-305 (2016). WB . Read more (PubMed: 26700621) »

    See all 3 Publications for this product

    发表研究结果有使用 ab34445？请让我们知道，以便我们可以引用本数据表中的参考文章。

    客户评价及客户问答

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    1 Review or Q&A

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    Votes: Highest First

    Immunocytochemistry/ Immunofluorescence abreview for Anti-Integrin alpha 1 antibody [TS2/7]

     Average
    Abreviews
    Application
    Immunocytochemistry/ Immunofluorescence
    Sample
    Human Cell (Tumour Cells)
    Specification
    Tumour Cells
    Fixative
    Paraformaldehyde
    Permeabilization
    No
    Blocking step
    Serum as blocking agent for 30 minute(s) · Concentration: 1% · Temperature: RT°C
    Read More
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    Username

    Dr. Sharon Sneddon

    Verified customer

    提交于 Jul 11 2008

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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