Anti-Insulin + Proinsulin抗体[D6C4] (ab8304)
Key features and details
- Mouse monoclonal [D6C4] to Insulin + Proinsulin
- Suitable for: ELISA
- Reacts with: Mouse, Rat, Cow, Human, Pig
- Isotype: IgG1
概述
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产品名称
Anti-Insulin + Proinsulin抗体[D6C4]
参阅全部 Insulin + Proinsulin 一抗 -
描述
小鼠单克隆抗体[D6C4] to Insulin + Proinsulin -
宿主
Mouse -
特异性
Specific for insulin and proinsulin.
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经测试应用
适用于: ELISAmore details -
种属反应性
与反应: Mouse, Rat, Cow, Human, Pig -
免疫原
Human insulin.
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常规说明
Kd for this antibody is 8.1 x 10-8M.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: 99.91% PBS -
Concentration information loading...
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纯度
Protein A purified -
Primary antibody说明
Detection of both insulin and proinsulin. -
克隆
单克隆 -
克隆编号
D6C4 -
骨髓瘤
unknown -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Affibody® Molecule
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Compatible Secondaries
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Conjugation kits
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Isotype control
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sELISA pair antibody
应用
应用 | Ab评论 | 说明 |
---|---|---|
ELISA | (1) |
Use a concentration of 10 µg/ml.
|
说明 |
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ELISA
Use a concentration of 10 µg/ml. |
靶标
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相关性
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Defects in insulin are the cause of familial hyperproinsulinemia. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 280829 Cow
- Entrez Gene: 3630 Human
- Entrez Gene: 16333 Mouse
- Entrez Gene: 16334 Mouse
- Entrez Gene: 24505 Rat
- Omim: 176730 Human
- SwissProt: P01317 Cow
- SwissProt: P01308 Human
see all -
别名
- ILPR antibody
- ins antibody
- Insulin antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (30)
ab8304 被引用在 30 文献中.
- Southam K et al. Development and characterisation of a rat model that exhibits both metabolic dysfunction and neurodegeneration seen in type 2 diabetes. J Physiol 600:1611-1630 (2022). PubMed: 35128667
- Huang R et al. Retinol-Binding Protein 4 Activates STRA6, Provoking Pancreatic ß-Cell Dysfunction in Type 2 Diabetes. Diabetes 70:449-463 (2021). PubMed: 33199363
- Suthamwong P et al. Administration of mulberry leaves maintains pancreatic ß-cell mass in obese/type 2 diabetes mellitus mouse model. BMC Complement Med Ther 20:136 (2020). PubMed: 32375753
- Viviano J et al. ERp29 as a regulator of Insulin biosynthesis. PLoS One 15:e0233502 (2020). PubMed: 32433667
- Yang SY et al. Prevascularization-free Primary Subcutaneous Transplantation of Xenogeneic Islets Coencapsulated With Hepatocyte Growth Factor. Transplant Direct 6:e620 (2020). PubMed: 33134496