HRP Anti-Insulin + Proinsulin抗体[D3E7] (ab28063)
Key features and details
- HRP Mouse monoclonal [D3E7] to Insulin + Proinsulin
- Suitable for: ELISA, IHC-Fr, IHC-P, Sandwich ELISA
- Reacts with: Mouse, Rat, Cow, Human, Pig
- Conjugation: HRP
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
HRP Anti-Insulin + Proinsulin抗体[D3E7]
参阅全部 Insulin + Proinsulin 一抗 -
描述
HRP小鼠单克隆抗体[D3E7] to Insulin + Proinsulin -
宿主
Mouse -
偶联物
HRP -
特异性
Kd for this antibody is 6.3 x 10-8M. This antibody is specific for both insulin and proinsulin -
经测试应用
适用于: ELISA, IHC-Fr, IHC-P, Sandwich ELISAmore details -
种属反应性
与反应: Mouse, Rat, Cow, Human, Pig -
免疫原
Human insulin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.40
Preservative: 0.05% Proclin 300
Constituents: 0.8% Sodium chloride, 0.02% Potassium chloride, 0.18% Dibasic monohydrogen sodium phosphate, 0.024% Monobasic dihydrogen potassium phosphate -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
D3E7 -
同种型
IgG1 -
轻链类型
kappa -
研究领域
相关产品
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Affibody® Molecule
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Alternative Versions
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-
sELISA pair antibody
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab28063于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
ELISA | (1) |
Use at an assay dependent concentration.
|
IHC-Fr |
Use at an assay dependent concentration.
|
|
IHC-P |
Use at an assay dependent concentration. PubMed: 24594640
|
|
Sandwich ELISA |
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [D6C4] to Insulin + Proinsulin (ab8304).
Can be used as Detection antibody with recommended pair. |
说明 |
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ELISA
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. PubMed: 24594640 |
Sandwich ELISA
Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Mouse monoclonal [D6C4] to Insulin + Proinsulin (ab8304). Can be used as Detection antibody with recommended pair. |
靶标
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相关性
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Defects in insulin are the cause of familial hyperproinsulinemia. -
细胞定位
Secreted -
数据库链接
- Entrez Gene: 280829 Cow
- Entrez Gene: 3630 Human
- Entrez Gene: 16333 Mouse
- Entrez Gene: 16334 Mouse
- Entrez Gene: 24505 Rat
- Omim: 176730 Human
- SwissProt: P01317 Cow
- SwissProt: P01308 Human
see all -
别名
- ILPR antibody
- ins antibody
- Insulin antibody
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab28063 被引用在 3 文献中.
- Kim J et al. 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis. Mol Cell Biol 39:N/A (2019). PubMed: 31481450
- Kim J et al. HX-1171 attenuates pancreatic ß-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model. Oncotarget 9:24260-24271 (2018). PubMed: 29849938
- Xiao F et al. Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2r?null mice. PLoS One 9:e90387 (2014). IHC-P . PubMed: 24594640