Anti-ING3抗体(ab84645)

概述

  • 产品名称Anti-ING3抗体
    参阅全部 ING3 一抗
  • 描述
    兔多克隆抗体to ING3
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide designed within residues: MDQLEQRVSE FFMNAKKNKP EWREEQMASI KKDYYKALED ADEKVQLANQ , corresponding to N terminal amino acids 36-85 of Human ING3 (NP_06944)

  • 阳性对照
    • HepG2 cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab84645 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性ING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure. ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • 1300013A07Rik antibody
    • Eaf 4 antibody
    • Eaf4 antibody
    • FLJ20089 antibody
    • ING 2 antibody
    • ING 3 antibody
    • ING2 antibody
    • Inhibitor of growth family member 3 antibody
    • Inhibitor of growth protein 3 antibody
    • MEAF4 antibody
    • p47 ING 3 antibody
    • p47 ING3 antibody
    • p47 regulator protein antibody
    • p47ING3 antibody
    • p47ING3 protein antibody
    see all

Anti-ING3 antibody 图像

  • Anti-ING3 antibody (ab84645) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 47 kDa
    Observed band size : 47 kDa
    Additional bands at : 31 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placenta tissue labelling ING3 with ab84645 at 5µg/ml.

Anti-ING3 antibody (ab84645)参考文献

ab84645 has not yet been referenced specifically in any publications.

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Merci d'avoir pris le temps de répondre à nos questions et de nous avoir contactés. Je suis désolée d'apprendre que vous avez eu des difficultés à obtenir de bons résultats avec ab84645.
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Merci d'avoir pris le temps de nous envoyer votre protocole. Je suis désolée d'apprendre qu’ab84645 ne vous donne pas de bons résultats en western blot.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"