Anti-Influenza Virus NS1A Binding Protein抗体(ab22846)

概述

  • 产品名称Anti-Influenza Virus NS1A Binding Protein抗体
    参阅全部 Influenza Virus NS1A Binding Protein 一抗
  • 描述
    兔多克隆抗体to Influenza Virus NS1A Binding Protein
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Pig
  • 免疫原

    A 14-22 amino acid region within synthetic peptide: MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSP, corresponding to intracellular amino acids 1-55 of Human Influenza Virus NS1A Binding Protein

  • 阳性对照
    • HepG2 cell lysate for western blots and human stomach cells for immunohistochemistry

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab22846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 71 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use at an assay dependent concentration.

靶标

  • 相关性NS1ABP plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats and is known to protect cells from cell death induced by actin destabilization. Interacts with NS/Influenza virus NS1A protein and is believed to mediate the inhibition of its splicing activity. It is usually associated with actin filaments (related to speckle domains) but following Influenza Avirus infection, NS1ABP presents a more diffuse distribution in the nucleoplasm
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • Aryl hydrocarbon receptor associated 3 antibody
    • DKFZp686K06216 antibody
    • FLARA 3 antibody
    • FLARA3 antibody
    • HSPC068 antibody
    • IVNS1ABP antibody
    • IVNS1ABP protein antibody
    • KIAA0850 antibody
    • NCX downstream gene 1 antibody
    • ND 1 antibody
    • ND1 antibody
    • NS 1 antibody
    • NS1 antibody
    • NS1 binding protein antibody
    • NS1 binding protein like protein antibody
    • NS1 BP antibody
    • NS1BP antibody
    see all

Anti-Influenza Virus NS1A Binding Protein antibody 图像

  • Anti-Influenza Virus NS1A Binding Protein antibody (ab22846) at 2 µg/ml + HepG2 whole cell lysate (ab7900)

    Predicted band size : 71 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
  • Epitheial cells of fundic glands (indicated by arrow) show positive labelling of anti-influenza virus NS1A binding protein. The antibody concentration ranged from 4.0-8.0µg/ml. The magnification of the image is 400X.

Anti-Influenza Virus NS1A Binding Protein antibody (ab22846)参考文献

ab22846 has not yet been referenced specifically in any publications.

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