Anti-Influenza A Virus M2 Protein抗体(ab94925)

概述

  • 产品名称Anti-Influenza A Virus M2 Protein抗体
    参阅全部 Influenza A Virus M2 Protein 一抗
  • 描述
    兔多克隆抗体to Influenza A Virus M2 Protein
  • 特异性ab94925 detects Influenza A Virus M2 Protein. It may crossreact with M2 protein from other strains of influenza.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Other
  • 免疫原

    A 13 amino acid peptide from the N terminus of Influenza A Virus M2 Protein.

性能

应用

Our Abpromise guarantee covers the use of ab94925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 11 kDa.

靶标

  • 相关性The Matrix protein M2 forms a protons channel. When the environmental pH is lower than a threshold, the M2 channel is activated and selectively transports protons accross the membrane from the extracellular side to the cytoplasmic side. It is crucial for the uncoating process. When the virion is internalized into the endosome the channel can acidify the virion interior, promoting the dissociation of the viral matrix protein (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell’s nucleus. For some influenza virus subtypes, the M2 channel can elevate the intravesicular pH of the trans Golgi network, preventing the viral protein haemagglutinin, which is transported to the cell surface through the trans Golgi network, from incorrect maturation in an otherwise low pH environment.
  • 细胞定位Virion membrane. Apical cell membrane; Single-pass type III membrane protein.
  • 别名
    • Influenza A virus matrix protein M2 antibody
    • M antibody
    • M2 antibody
    • Matrix protein 2 antibody
    • Membrane ion channel M2 antibody
    • Membrane protein M2 antibody
    • Proton channel protein M2 antibody
    see all

Anti-Influenza A Virus M2 Protein antibody (ab94925)参考文献

ab94925 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application ELISA
Sample A/Sw/SK/2001 (H1N1) influenza Purified protein (Purified inactivated human H3N2 influenza virus)
Specification Purified inactivated human H3N2 influenza virus
Type Indirect
Username

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Verified customer

提交于 Nov 02 2016

Thank you for your enquiry and interest in our products.
There is 92.31% homology between the immunogen used for ab94925 (Anti-Influenza A Virus M2 Protein antibody) and ACP44185 - EMBL: Matrix protein 2 - Influenza A virus (A/California/07/2009(H...

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Thank you for your enquiry.

The immunogens used to produce ab94925 and ab56086 consist of a small 15-20 amino acid peptide from Influenza A virus M2 protein. These peptides are not His tagged.

I hope this is helpful. Please contact ...

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Following my colleague's email sent on Friday 23rd of December (CCE 3385949), we have been informed that there is 84% homology between the immunogen for ab94925 (www.abcam.com/ab94925) and the customer's sequence: [******* ****]. I hope this informatio...

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Thank you very much for your inquiry. I have contacted the laboratory for information on the ab5416. However the laboratory has not tested this antibody neither on your strain. I did a sequence alignement of the immunogen and your sequence. Please see ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"