概述
- 产品名称Anti-Influenza A Virus M2 Protein抗体
参阅全部 Influenza A Virus M2 Protein 一抗 - 描述兔多克隆抗体to Influenza A Virus M2 Protein
- 特异性ab94925 detects Influenza A Virus M2 Protein. It may crossreact with M2 protein from other strains of influenza.
- 经测试应用适用于: WBmore details
- 种属反应性与反应: Other
- 免疫原
A 13 amino acid peptide from the N terminus of Influenza A Virus M2 Protein.
性能
- 形式Liquid
- 存放说明Shipped at 4°C. Store at +4°C.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... - 纯度Immunogen affinity purified
- 纯化说明Affinity chromatography purified via peptide column.
- 克隆多克隆
- 同种型IgG
- 研究领域
相关产品
- Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab94925 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use at an assay dependent dilution. Predicted molecular weight: 11 kDa. |
靶标
- 相关性The Matrix protein M2 forms a protons channel. When the environmental pH is lower than a threshold, the M2 channel is activated and selectively transports protons accross the membrane from the extracellular side to the cytoplasmic side. It is crucial for the uncoating process. When the virion is internalized into the endosome the channel can acidify the virion interior, promoting the dissociation of the viral matrix protein (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell’s nucleus. For some influenza virus subtypes, the M2 channel can elevate the intravesicular pH of the trans Golgi network, preventing the viral protein haemagglutinin, which is transported to the cell surface through the trans Golgi network, from incorrect maturation in an otherwise low pH environment.
- 细胞定位Virion membrane. Apical cell membrane; Single-pass type III membrane protein.
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别名
- Influenza A virus matrix protein M2 antibody
- M antibody
- M2 antibody
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Anti-Influenza A Virus M2 Protein antibody (ab94925)参考文献
ab94925 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"