Anti-Influenza A Nonstructural Protein 1抗体(ab91642)

概述

  • 产品名称Anti-Influenza A Nonstructural Protein 1抗体
    参阅全部 Influenza A Nonstructural Protein 1 一抗
  • 描述
    兔多克隆抗体to Influenza A Nonstructural Protein 1
  • 特异性Specific for the seasonal Influenza A Nonstructural Protein 1. Does not bind the corresponding Nonstructural Protein 1 from the swine flu Influenza A virus.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    Reacts with seasonal Influenza A H1N1 virus. Does not react with Swine flu Influenza A H1N1 virus.
  • 免疫原

    Synthetic peptide specific for the seasonal Influenza A H1N1 Nonstructural Protein 1 (ABP49398).

性能

应用

Our Abpromise guarantee covers the use of ab91642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. The virus has one of sixteen possible hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. In early 2009, a novel H1N1 swine-origin influenza (S-OIV) A virus was identified in specimens obtained from patients in Mexico and the United States. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the antiviral protein kinase PKR.
    • 细胞定位host cell cytoplasm and nucleus
    • 别名
      • Nonstructural protein 1 antibody
      • NS1 antibody
      • NS1A antibody

    Anti-Influenza A Nonstructural Protein 1 antibody (ab91642)参考文献

    ab91642 has not yet been referenced specifically in any publications.

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