Anti-Indoleamine 2, 3-dioxygenase抗体(ab106134)


  • 产品名称Anti-Indoleamine 2, 3-dioxygenase抗体
    参阅全部 Indoleamine 2, 3-dioxygenase 一抗
  • 描述
    兔多克隆抗体to Indoleamine 2, 3-dioxygenase
  • 特异性Does not bind to IDO2
  • 经测试应用适用于: WB, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A mixture of 3 peptides derived from Rat Indoleamine 2, 3-dioxygenase: MPHSQISPAEGSRRILEEY (1-19), LFSFPGGDCDKGFFLVSLMVE (155-176), and VKPSKQKPMGGHKSEEPS (359-376), conjugated to KLH.



Our Abpromise guarantee covers the use of ab106134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50. Predicted molecular weight: 45 kDa.
IHC-P 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IHC-Fr 1/50.


  • 功能Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
  • 通路Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.
  • 序列相似性Belongs to the indoleamine 2,3-dioxygenase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3-dioxygenase antibody
    • I23O1_HUMAN antibody
    • IDO 1 antibody
    • IDO antibody
    • IDO-1 antibody
    • IDO1 antibody
    • INDO antibody
    • indolamine 2,3 dioxygenase antibody
    • Indole 2 3 dioxygenase antibody
    • indoleamine 2 3 dioxygenase 1 antibody
    • indoleamine 2 3 dioxygenase antibody
    • Indoleamine 2,3-dioxygenase 1 antibody
    • Indoleamine pyrrole 2 3 dioxygenase antibody
    • Indoleamine-pyrrole 2 antibody
    see all

Anti-Indoleamine 2, 3-dioxygenase antibody (ab106134)参考文献

This product has been referenced in:
  • Bandeira LG  et al. Exogenous Tryptophan Promotes Cutaneous Wound Healing of Chronically Stressed Mice through Inhibition of TNF-a and IDO Activation. PLoS One 10:e0128439 (2015). Mouse . Read more (PubMed: 26057238) »
  • Wainwright DA  et al. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors. Clin Cancer Res 20:5290-301 (2014). Read more (PubMed: 24691018) »

See all 4 Publications for this product

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My name is Jeremy Kasanovand I'm helping Sybille with her emails while she is out of the office.

The antibody was tested by thelab which developed this antibodyfor cross reactivity with mouse IDO in Western blot. Unfortunately we have no deta...

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Thank you for your reply.

The information the lab sent me is all we have available. There is also a reference listed on the datasheet where human and rat tissue was used:

Hill M et al. Heme oxygenase-1 inhibits rat and human breast...

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I am very pleased to hear you would like to use ab106134 in mouse and send us an image of your results.

This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview with the imag...

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Thank you very much for your interest in ab106134 and for your patience.

Unfortunately I have not been able to obtain any more information on the tissue tested in mouse and I do not want for you to have to continue to wait for a response. Read More

I am very pleased to hear you would like to accept our offer and test ab55305 and ab106134 in monkey. These codes will give you 1 free primary antibody per code before the expiration date. To redeem this offer, please submit an Abreview for each antibo...

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