Anti-Indoleamine 2, 3-dioxygenase抗体(ab106134)

概述

  • 产品名称
    Anti-Indoleamine 2, 3-dioxygenase抗体
    参阅全部 Indoleamine 2, 3-dioxygenase 一抗
  • 描述
    兔多克隆抗体to Indoleamine 2, 3-dioxygenase
  • 特异性
    Does not bind to IDO2
  • 经测试应用
    适用于: WB, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A mixture of 3 peptides derived from Rat Indoleamine 2, 3-dioxygenase: MPHSQISPAEGSRRILEEY (1-19), LFSFPGGDCDKGFFLVSLMVE (155-176), and VKPSKQKPMGGHKSEEPS (359-376), conjugated to KLH.

性能

应用

Our Abpromise guarantee covers the use of ab106134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50. Predicted molecular weight: 45 kDa.
IHC-P 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IHC-Fr 1/50.

靶标

  • 功能
    Catalyzes the cleavage of the pyrrol ring of tryptophan and incorporates both atoms of a molecule of oxygen.
  • 通路
    Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.
  • 序列相似性
    Belongs to the indoleamine 2,3-dioxygenase family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3-dioxygenase antibody
    • I23O1_HUMAN antibody
    • IDO 1 antibody
    • IDO antibody
    • IDO-1 antibody
    • IDO1 antibody
    • INDO antibody
    • indolamine 2,3 dioxygenase antibody
    • Indole 2 3 dioxygenase antibody
    • indoleamine 2 3 dioxygenase 1 antibody
    • indoleamine 2 3 dioxygenase antibody
    • Indoleamine 2,3-dioxygenase 1 antibody
    • Indoleamine pyrrole 2 3 dioxygenase antibody
    • Indoleamine-pyrrole 2 antibody
    see all

Anti-Indoleamine 2, 3-dioxygenase antibody 图像

  • Heat inducing epitope retrieval is used as pre-treatment.  Blocking of the endogenous peroxidase is necessary to avoid unspecific background staining. 

Anti-Indoleamine 2, 3-dioxygenase antibody (ab106134)参考文献

This product has been referenced in:
  • Nagy-Grócz G  et al. The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat. Front Neurol 8:278 (2017). WB ; Rat . Read more (PubMed: 28659861) »
  • Lu X  et al. Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats. PLoS One 12:e0172339 (2017). Read more (PubMed: 28212441) »

See all 6 Publications for this product

Product Wall

My name is Jeremy Kasanovand I'm helping Sybille with her emails while she is out of the office.

The antibody was tested by thelab which developed this antibodyfor cross reactivity with mouse IDO in Western blot. Unfortunately we have no deta...

Read More

Thank you for your reply.

The information the lab sent me is all we have available. There is also a reference listed on the datasheet where human and rat tissue was used:

Hill M et al. Heme oxygenase-1 inhibits rat and human breast...

Read More

I am very pleased to hear you would like to use ab106134 in mouse and send us an image of your results.

This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview with the imag...

Read More

Thank you very much for your interest in ab106134 and for your patience.

Unfortunately I have not been able to obtain any more information on the tissue tested in mouse and I do not want for you to have to continue to wait for a response. Read More

I am very pleased to hear you would like to accept our offer and test ab55305 and ab106134 in monkey. These codes will give you 1 free primary antibody per code before the expiration date. To redeem this offer, please submit an Abreview for each antibo...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册