概述

  • 产品名称Anti-IMPDH2抗体
    参阅全部 IMPDH2 一抗
  • 描述
    小鼠多克隆抗体to IMPDH2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified), corresponding to amino acids 1-514 of Human IMPDH2

性能

应用

Our Abpromise guarantee covers the use of ab70045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

靶标

  • 功能Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • 组织特异性IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • 通路Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • 序列相似性Belongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • 翻译后修饰The N-terminus is blocked.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IMDH2_HUMAN antibody
    • IMP (inosine monophosphate) dehydrogenase 2 antibody
    • IMP dehydrogenase 2 antibody
    • IMP oxireductase 2 antibody
    • IMPD 2 antibody
    • IMPD2 antibody
    • IMPDH 2 antibody
    • IMPDH II antibody
    • IMPDH-II antibody
    • Impdh2 antibody
    • Inosine 5' monophosphate dehydrogenase 2 antibody
    • Inosine 5' phosphate dehydrogenase 2 antibody
    • Inosine monophosphate dehydrogenase type II antibody
    • Inosine-5''-monophosphate dehydrogenase 2 antibody
    see all

Anti-IMPDH2 antibody 图像

  • All lanes : Anti-IMPDH2 antibody (ab70045) at 1/500 dilution

    Lane 1 : IMPDH2-transfected 293T cell line lysate
    Lane 2 : non-transfected 293T cell line lysate


    Predicted band size : 56 kDa
    Observed band size : 56 kDa

Anti-IMPDH2 antibody (ab70045)参考文献

ab70045 has not yet been referenced specifically in any publications.

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