概述

  • 产品名称Anti-IMPACT抗体
    参阅全部 IMPACT 一抗
  • 描述
    小鼠多克隆抗体to IMPACT
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein (purified), corresponding to amino acids 1-320 of Human IMPACT

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab72444 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 36 kDa.

靶标

  • 功能Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.
  • 组织特异性Widely expressed. Expressed at high level in brain.
  • 序列相似性Belongs to the IMPACT family.
    Contains 1 RWD domain.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IMPACT antibody
    • Impact homolog (mouse) antibody
    • Impact homolog antibody
    • impact RWD domain protein antibody
    • IMPCT_HUMAN antibody
    • Imprinted and ancient gene protein homolog antibody
    • MGC33718 antibody
    • Protein IMPACT antibody
    • RWD domain containing 5 antibody
    • RWDD5 antibody
    see all

Anti-IMPACT antibody 图像

  • Anti-IMPACT antibody (ab72444) + Rat brain

    Secondary
    HRP-conjugated goat anti-mouse IgG (H&L)

    Predicted band size : 36 kDa
  • All lanes : Anti-IMPACT antibody (ab72444)

    Lane 1 : IMPACT transfected lysate (human 293T cell line)
    Lane 2 : Non-transfected lysate


    Predicted band size : 36 kDa

Anti-IMPACT antibody (ab72444)参考文献

This product has been referenced in:
  • Habibi D  et al. High expression of IMPACT protein promotes resistance to indoleamine 2,3-dioxygenase-induced cell death. J Cell Physiol 225:196-205 (2010). WB ; Human . Read more (PubMed: 20648630) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab72444.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"