概述

  • 产品名称Anti-IMP5抗体
  • 描述
    兔多克隆抗体to IMP5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 575-624 (NPGEDTTEIV TISENEATNP EDRSDSSEGW SDAHLDPNEL PFIPPGASEE) of Human IMP5 (NP_787078)

  • 阳性对照
    • Human fetal thymus lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab98157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the peptidase A22B family.
    Contains 1 PA (protease associated) domain.
  • 结构域The PAL motif is required for normal active site conformation. The catalytic domains embedded in the membrane are in the opposite orientation to that of the presenilin protein family; therefore, it is predicted to cleave type II-oriented substrate peptides like the prototypic protease SPP.
  • 翻译后修饰Glycosylated.
  • 细胞定位Endoplasmic reticulum membrane. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IMP-5 antibody
    • Intramembrane protease 5 antibody
    • Signal peptide peptidase-like 2C antibody
    • SPP-like 2C antibody
    • SPP2C_HUMAN antibody
    • SPPL2C antibody
    see all

Anti-IMP5 antibody 图像

  • Anti-IMP5 antibody (ab98157) at 1 µg/ml + Human fetal thymus lysate at 10 µg

    Predicted band size : 75 kDa

Anti-IMP5 antibody (ab98157)参考文献

ab98157 has not yet been referenced specifically in any publications.

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