概述

  • 产品名称Iloprost
  • 描述
    Prostaglandin (PGI2) analog
  • 别名
    • ZK 36374
  • 生物学描述Prostaglandin (PGI2) analog. Binds with high affinity to the human recombinant IP, EP1 and EP3 receptors (Ki values are 11 (IP and EP1) and 56 nM (EP3)). Higher selectivity over other prostanoid receptors.
  • 纯度> 97%

性能

  • 化学名称(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid
  • 分子量360.49
  • 化学结构Chemical Structure
  • 分子式C22H32O4
  • CAS编号78919-13-8
  • 存放说明Store at -20°C (desiccating conditions).
  • 溶解度概述Supplied in methyl acetate (5 mg/ml)
  • 处理

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESO[C@@H]1C[C@H](C/2)[C@H](CC2=CCCCC(O)=O)[C@H]1/C=C/[C@@H](O)C(C)CC#CC
  • 来源

    Synthetic

  • 研究领域

    Iloprost (ab120911)参考文献

    This product has been referenced in:
    • Della Bella S  et al. Novel mode of action of iloprost: in vitro down-regulation of endothelial cell adhesion molecules. Prostaglandins Other Lipid Mediat 65:73-83 (2001). Read more (PubMed: 11403500) »
    • Abramovitz M  et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483:285-93 (2000). Read more (PubMed: 10634944) »

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