生物学描述Prostaglandin (PGI2) analog. Binds with high affinity to the human recombinant IP, EP1 and EP3 receptors (Ki values are 11 (IP and EP1) and 56 nM (EP3)). Higher selectivity over other prostanoid receptors.
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Della Bella S et al. Novel mode of action of iloprost: in vitro down-regulation of endothelial cell adhesion molecules. Prostaglandins Other Lipid Mediat65:73-83 (2001).
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Abramovitz M et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta1483:285-93 (2000).
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