概述

  • 产品名称Anti-ILKAP抗体
    参阅全部 ILKAP 一抗
  • 描述
    兔多克隆抗体to ILKAP
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    synthesized peptide derived from the internal of human ILKAP.

  • 阳性对照
    • Extracts from COS7 cells. Colon carcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab70019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
ELISA 1/20000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
  • 组织特异性Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues.
  • 序列相似性Belongs to the PP2C family.
    Contains 1 PP2C-like domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp434J2031 antibody
    • FLJ10181 antibody
    • ILKAP antibody
    • ILKAP_HUMAN antibody
    • ILKAP2 antibody
    • ILKAP3 antibody
    • Integrin linked kinase associated phosphatase antibody
    • Integrin linked kinase associated serine/threonine phosphatase 2C antibody
    • Integrin linked kinase associated serine/threonine phosphatase antibody
    • Integrin-linked kinase-associated serine/threonine phosphatase 2C antibody
    • MGC4846 antibody
    • PP2C DELTA antibody
    • Protein phosphatase 2c delta isozyme antibody
    see all

Anti-ILKAP antibody 图像

  • All lanes : Anti-ILKAP antibody (ab70019)

    Lane 1 : extracts from COS7 cells
    Lane 2 : extracts from COS7 cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 46 kDa
    Observed band size : 46 kDa
    Additional bands at : 36 kDa,50 kDa,60 kDa. We are unsure as to the identity of these extra bands.
  • immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using 1/50 ab70019. Right: with antibody pre-treatment with immunizing peptide

Anti-ILKAP antibody (ab70019)参考文献

ab70019 has not yet been referenced specifically in any publications.

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