概述

  • 产品名称
  • 描述
    兔多克隆抗体to ILF1
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residue 635 and 660 of Human ILF1 (NP_004505.2).

  • 阳性对照
    • Human Anaplastic Thyroid Carcinoma, Breast Carcinoma, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma and Small Cell Lung Cancer.

性能

应用

Our Abpromise guarantee covers the use of ab84761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements.
    • 组织特异性
      Expressed in both lymphoid and non-lymphoid cells.
    • 序列相似性
      Contains 1 FHA domain.
      Contains 1 fork-head DNA-binding domain.
    • 结构域
      The C-terminal part of the DNA-binding domain may contribute to DNA recognition specificity.
    • 翻译后修饰
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位
      Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cellular transcription factor ILF 1 antibody
      • Cellular transcription factor ILF-1 antibody
      • Cellular transcription factor ILF1 antibody
      • Forkhead box K2 antibody
      • Forkhead box protein K2 antibody
      • FOX K1 antibody
      • FOX K2 antibody
      • FOXK 1 antibody
      • FOXK 2 antibody
      • FOXK1 antibody
      • foxk2 antibody
      • FOXK2_HUMAN antibody
      • ILF 1 antibody
      • ILF antibody
      • Interleukin enhancer binding factor 1 antibody
      • Interleukin enhancer-binding factor 1 antibody
      see all

    图片

    • Detection of Human ILF1 by Immunohistochemistry in formalin-fixed, paraffin-embedded human small cell lung cancer using ab84761, at 1/250 dilution, and DAB staining.

    文献

    This product has been referenced in:
    • Liu Y  et al. FOXK2 transcription factor suppresses ERa-positive breast cancer cell growth through down-regulating the stability of ERa via mechanism involving BRCA1/BARD1. Sci Rep 5:8796 (2015). Read more (PubMed: 25740706) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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