概述

  • 产品名称Anti-IL9R抗体
    参阅全部 IL9R 一抗
  • 描述
    兔多克隆抗体to IL9R
  • 特异性ab61196 detects endogenous levels of total IL9R protein.
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from human IL9R around the phosphorylation site of serine 519.

  • 阳性对照
    • Human lymph node tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab61196 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab61196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
IHC-P 1/50 - 1/100.

靶标

  • 功能This is a receptor for interleukin-9.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • 结构域The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 细胞定位Cell membrane. Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD129 antibody
    • IL-9 receptor antibody
    • IL-9R antibody
    • Il9r antibody
    • IL9R_HUMAN antibody
    • IL9RX antibody
    • IL9RY antibody
    • Interleukin 9 receptor antibody
    • Interleukin-9 receptor antibody
    see all

Anti-IL9R antibody 图像

  • ab61196 at 1/50 dilution staining IL9R in human lymph node by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.

Anti-IL9R antibody (ab61196)参考文献

This product has been referenced in:
  • Vieyra-Garcia PA  et al. STAT3/5-Dependent IL9 Overexpression Contributes to Neoplastic Cell Survival in Mycosis Fungoides. Clin Cancer Res 22:3328-39 (2016). IHC-P ; Human . Read more (PubMed: 26851186) »
  • Singh TP  et al. Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis. PLoS One 8:e51752 (2013). IHC-P ; Human . Read more (PubMed: 23335955) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"