概述

  • 产品名称Anti-IL3RB抗体[RM0112-42A7]
    参阅全部 IL3RB 一抗
  • 描述
    大鼠单克隆抗体[RM0112-42A7] to IL3RB
  • 特异性This antibody detects mouse IL3RB, but not IL3RA in Western blotting.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Mouse recombinant protein of the extracellular domain of IL3RB.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明The IgG fraction of culture supernatant was purified by Protein A affinity chromatography
  • 克隆单克隆
  • 克隆编号RM0112-42A7
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab86743 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 97 kDa.

靶标

  • 功能High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
  • 序列相似性Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 2 fibronectin type-III domains.
  • 结构域The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • /granulocyte-macrophage colony-stimulating factor receptor, beta antibody
    • Beta-C antibody
    • CD131 antibody
    • CDw131 antibody
    • Colony stimulating factor 2 receptor beta antibody
    • Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage) antibody
    • Common beta chain antibody
    • Csf2rb antibody
    • Cytokine receptor common beta chain antibody
    • Cytokine receptor common beta chain precursor (CDw131 antigen) antibody
    • Cytokine receptor common subunit beta antibody
    • GM CSF/IL 3/IL 5 receptor common beta chain antibody
    • GM-CSF/IL-3/IL-5 receptor common beta subunit antibody
    • IL3RB antibody
    • IL3RB_HUMAN antibody
    • IL5RB antibody
    • Interleukin 3 receptor, beta antibody
    • Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity) antibody
    • Interleukin 5 receptor, beta antibody
    • SMDP5 antibody
    • stimulating factor 3 receptor, beta (high affinity) antibody
    see all

Anti-IL3RB antibody [RM0112-42A7] (ab86743)参考文献

This product has been referenced in:
  • Egea L  et al. GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J Immunol 190:1702-13 (2013). Read more (PubMed: 23325885) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"