Anti-IL-3RB抗体[RM0112-42A7] (ab86743)
Key features and details
- Rat monoclonal [RM0112-42A7] to IL-3RB
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG1
概述
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产品名称
Anti-IL-3RB抗体[RM0112-42A7]
参阅全部 IL-3RB 一抗 -
描述
大鼠单克隆抗体[RM0112-42A7] to IL-3RB -
宿主
Rat -
特异性
This antibody detects mouse IL3RB, but not IL3RA in Western blotting. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Fusion protein corresponding to Mouse IL-3RB aa 1-450.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
Protein A purified -
纯化说明
The IgG fraction of culture supernatant was purified by Protein A affinity chromatography -
克隆
单克隆 -
克隆编号
RM0112-42A7 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab86743于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration.
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说明 |
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WB
Use at an assay dependent concentration. |
靶标
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功能
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. -
序列相似性
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 2 fibronectin type-III domains. -
结构域
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 12983 Mouse
- SwissProt: P26955 Mouse
- Unigene: 235324 Mouse
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别名
- Beta-C antibody
- CD131 antibody
- CDw131 antibody
see all
数据表及文件
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Datasheet download
文献 (1)
ab86743 被引用在 1 文献中.
- Egea L et al. GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J Immunol 190:1702-13 (2013). PubMed: 23325885