概述

  • 产品名称Anti-IL3RB抗体[EP1037Y]
    参阅全部 IL3RB 一抗
  • 描述
    兔单克隆抗体[EP1037Y] to IL3RB
  • 经测试应用适用于: WB, IHC-Pmore details
    不适用于: Flow Cyt,ICC or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues in the C-terminus of human IL3RB was used as an immunogen.

  • 阳性对照
    • TF1 cell lysate; Human lymphoma tissue.
  • 常规说明

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 纯度Tissue culture supernatant
  • 纯化说明Supplied as cell supernatant in storage buffer.
  • 克隆单克隆
  • 克隆编号EP1037Y
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab52609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/5000. Predicted molecular weight: 130 kDa.
IHC-P 1/100 - 1/250.
  • 应用说明Is unsuitable for Flow Cyt,ICC or IP.
  • 靶标

    • 功能High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
    • 序列相似性Belongs to the type I cytokine receptor family. Type 4 subfamily.
      Contains 2 fibronectin type-III domains.
    • 结构域The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
      The box 1 motif is required for JAK interaction and/or activation.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • /granulocyte-macrophage colony-stimulating factor receptor, beta antibody
      • Beta-C antibody
      • CD131 antibody
      • CDw131 antibody
      • Colony stimulating factor 2 receptor beta antibody
      • Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage) antibody
      • Common beta chain antibody
      • Csf2rb antibody
      • Cytokine receptor common beta chain antibody
      • Cytokine receptor common beta chain precursor (CDw131 antigen) antibody
      • Cytokine receptor common subunit beta antibody
      • GM CSF/IL 3/IL 5 receptor common beta chain antibody
      • GM-CSF/IL-3/IL-5 receptor common beta subunit antibody
      • IL3RB antibody
      • IL3RB_HUMAN antibody
      • IL5RB antibody
      • Interleukin 3 receptor, beta antibody
      • Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity) antibody
      • Interleukin 5 receptor, beta antibody
      • SMDP5 antibody
      • stimulating factor 3 receptor, beta (high affinity) antibody
      see all

    Anti-IL3RB antibody [EP1037Y] 图像

    • Anti-IL3RB antibody [EP1037Y] (ab52609) at 1/5000 dilution + TF1 cell lysate at 10 µg

      Secondary
      HRP-labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 130 kDa
    • Immunohistochemical staining of paraffin-embedded human lymphoma using at a dilution of 1/100-1/250.

    Anti-IL3RB antibody [EP1037Y] (ab52609)参考文献

    This product has been referenced in:
    • Medana IM  et al. Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria. Malar J 8:261 (2009). IHC-P ; Human . Read more (PubMed: 19930602) »
    • Schroeder JT  et al. Human basophils secrete IL-3: evidence of autocrine priming for phenotypic and functional responses in allergic disease. J Immunol 182:2432-8 (2009). Read more (PubMed: 19201898) »

    See all 2 Publications for this product

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    Thank you for contacting us and your interest in our products.


    I can confirm that lot number GR33135-1 of Anti-IL3RB antibody [EP1037Y] (ab52609) is of a concentration of 2.763 mg/mL.


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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"