Anti-IL36 gamma抗体(ab116281)

概述

  • 产品名称Anti-IL36 gamma抗体
    参阅全部 IL36 gamma 一抗
  • 描述
    兔多克隆抗体to IL36 gamma
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide corresponding to Human IL36 gamma aa 100 to the C-terminus conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q9NZH8

  • 阳性对照
    • This antibody gave a positive signal in Human Tonsil tissue lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS

    Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab116281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).

靶标

  • 功能Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
  • 组织特异性Highly expressed in tissues containing epithelial cells: skin, lung, stomach and esophagus. In skin is expressed only in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Up-regulated in lesional psoriasis skin.
  • 序列相似性Belongs to the IL-1 family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IL 1 epsilon antibody
    • IL 1 related protein 2 antibody
    • IL 1(EPSILON) antibody
    • IL 1F9 antibody
    • IL 1H1 antibody
    • IL 1RP2 antibody
    • IL-1 epsilon antibody
    • IL-1-related protein 2 antibody
    • IL-1F9 antibody
    • IL-1H1 antibody
    • IL-1RP2 antibody
    • IL1E antibody
    • Il1f9 antibody
    • IL1F9_HUMAN antibody
    • IL1H1 antibody
    • IL1RP2 antibody
    • IL36G antibody
    • Interleukin 1 epsilon antibody
    • Interleukin 1 family member 9 antibody
    • Interleukin 1 homolog 1 antibody
    • Interleukin 1 related protein 2 antibody
    • Interleukin 36 gamma antibody
    • Interleukin-1 epsilon antibody
    • Interleukin-1 family member 9 antibody
    • Interleukin-1 homolog 1 antibody
    see all

Anti-IL36 gamma antibody 图像

  • Anti-IL36 gamma antibody (ab116281) at 1 µg/ml + Tonsil (Human) Tissue Lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 19 kDa
    Observed band size : 19 kDa
    Additional bands at : 90 kDa (possible non-specific binding).

    Exposure time : 8 minutes

    This blot was produced using a 4-12% Bis-tris gel under the MES buffer system. The gel was run at 200V for 35 minutes before being transferred onto a Nitrocellulose membrane at 30V for 70 minutes. The membrane was then blocked for an hour using 5% Bovine Serum Albumin before being incubated with ab116281 overnight at 4°C. Antibody binding was detected using an anti-rabbit antibody conjugated to HRP, and visualised using ECL development solution.

Anti-IL36 gamma antibody (ab116281)参考文献

ab116281 has not yet been referenced specifically in any publications.

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